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The effect of cystamine on oxidative phosphorylation in the spleen of irradiated albino rats

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

In this work, performed on albino rats, the author demonstrated that x-irradiation in a dose of 600 r.leads to the change of the oxidative phosphorylation level in the spleen. In these conditions there occurs a drop of the phosphorylation level and its dissociation from the tissue respiration. Administration of cystamine (in prophylactic effective doses) to the animals prior to the irradiation with ionizing radiation decreases the changes of the oxidative phosphorylation in the spleen, without eliminating them completely.

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Authors and Affiliations

  1. Order of Lenin S. M. Kirov Military Medical Academy, Leningrad

    V. G. Vladimirov

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  1. V. G. Vladimirov
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Vladimirov, V.G. The effect of cystamine on oxidative phosphorylation in the spleen of irradiated albino rats. Bull Exp Biol Med 54, 1236–1238 (1963). https://doi.org/10.1007/BF00785595

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  • DOI: https://doi.org/10.1007/BF00785595

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