Summary
A survey of serum Pi, Cp, Hp and Tf was carried out in 104 Bengali Hindu Mahishya and 123 Bengali Muslim of West Bengal, India.
The frequency of PiM allel was very high (over 99%) in both populations. The alleles CpA or CpB are rare in Indian populations, but have been detected in the present study. The Hp1 gene frequencies obtained in both populations was within the range so far found in other Indian populations (5% to 22%). Any Tf variant other than CC is rare in Indian populations but an appreciable frequency of CD (nearly 3%) was detected in both our populations.
The two groups studied here appear to be homogenous in respect of the distribution of the alleles in the various systems, except for haptoglobin (ϰ=5.533, 1 df).
Zusammenfassung
Bei 104 Hindu-Mahishya-Bengalen und 123 Muslim-Bengalen aus West-Bengalen (Indien) wurde eine Erhebung über die Serumgruppen Pi, Cp, Hp und Tf durchgeführt.
Die Häufigkeit des PiM-Allels ist sehr hoch (über 99%) in beiden Bevölkerungen. Die Allele CpA oder CpB sind in der indischen Bevölkerung selten; sie wurden jedoch in dieser Studie gefunden. Die Hp1-Genhäufigkeiten in beiden Bevölkerungen bewegen sich in dem Bereich, der bisher schon für andere indische Bevölkerungen wurde (5–22%). Außer CC sind alle Tf-Varianten in der indischen Bevölkerung selten; jedoch fand sich in den beiden untersuchten Bevölkerungen eine nicht unbeträchtliche Häufigkeit von CD (fast 3%).
Die beiden untersuchten Gruppen sind homogen bezüglich der Verteilung der Allele in den verschiedenen Systemen; eine Ausnahme macht hier nur das Haptoglobin (ϰ=5.533, 1df).
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References
Ananthakrishman, R., Kirk, R. L.: The distribution of some serum proteins and enzyme group systems in two endogamous groups in. S. India. Ind. J. Med. Res. 57, 1011–1017 (1969)
Baxi, A. J., Camòens, H.: Transferrin polymorphism in Indians. Proc. Indian Soc. Hemat. blood Transf. 41–43 (1970)
Blake, N. M., Kirk, R. L., Mcdernied, E. M., Keichi Omoto, Ahuja, Y. R.: The distribution of serum proteins and enzyme group systems among North Indians. Hum. Hered. 21, 440–457 (1971)
Chopra, V. P.: Studies on serum groups in the Kumaon region, India. Humangenetik 10, 35–43 (1970)
Fagerhol, M. K., Braned, M.: Classification of human serum prealbumins after starch gel electropheresis. Acta path. microbiol. scand. 68, 434–438 (1966)
Giblett, B. R.: The plasma transferrin. In: Bearu, A. G., Steinberg, A. G., (Eds.), Progress in medical genetics, Vol. 2, p. 34. New York: Grune and Stratan 1962
Halmberg, C. C., Laurell, C. B.: Investigation in serum copper II isolation of the copper containing protein and a description of some of its properties. Acta Chem. scand. 2, 550–556 (1948)
Kellermann, G., Walter, H.: Investigation on the population genetics of the α1 polymorphism. Humangenetik 10, 145–150 (1970)
Kirk, R. L.: The world distribution of transferrin variants and some unsolved problems. Acta Genet. med. (Roma)17, 613–639 (1968)
Kirk, R. L., Lai, L. Y. C.: The distribution of haptoglobin and transferrin groups in South East Asia. Acta Genet. (Basel) 11, 97–105 (1961)
Kirk, R. L., Lai, L. Y. C., Vos, G. H., Wiskremasinghe, R. L., Perera, J. B.: The blood and serum groups of selected population in South India and Ceylone. Amer. J. Phys. Anthrop. 20, 485–497 (1962)
McDermid, E. M.: Variants in serum albumin and ceruloplasmin in population from Australia, New Guinea, South Africa and India. Aust. J. exp. Biol. med. Sci. 49, 389–312 (1971)
Mukherjee, B. N., Das, S. K.: The haptoglobin and transferrin types in West Bengal and a case of haptoglobin Johnson. Hum. Hered. 20, 200–214 (1970)
Polonovski, M., Jayle, M. F.: Sur la preparation dune nouville fraction des proteines plasmatiquies. I'haptoglobins. C.R. Acad. Sci. (Paris) 211, 517 (1940)
Poulik, M. D.: Starch gel electrophoresis in discontineous system of buffer. Nature (Lond.) 180, 1477–1479 (1957)
Smithies, O.: Variations in human serum β-globulins. Nature (Lond.)180, 1482 (1957)
Tiwari, S. C.: The frequencies of serum haptoglobin and transferrin types in a Punjabi population. Anthropologist VIII,23–28 (1961)
Walter, H.: Notes on the distribution of some serum protein polymorphism in India. Proced., S.C. Roy centenary cellebration. Ranchi, 1971, in press
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Mukherjee, B.N., Das, S.K. & Kellermann, G. Study of some serum group systems in the Mahishyas and the Muslims in 24-Parganas district, West Bengal. Hum Genet 21, 27–32 (1974). https://doi.org/10.1007/BF00278561
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DOI: https://doi.org/10.1007/BF00278561