Summary
After monocular injections of tritiated tracer precursors and transneuronal transport of tritiated compounds, a continuous band of radioactivity in layer IV of striate cortex of Callithrix jachus (Callithricidae, New World primates) indicated a complete desegregation of the crossed and uncrossed retino-cortical pathways. Comparison with the organization of these pathways in other primates suggests that a segregation of the retino-cortical pathways of opposite ocularities into alternating ocular dominance columns in striate cortex has developed independently in the different primate lines. The significance is discussed of the weak labeling of the region of area 17 representing the central retina as compared to the representation of the peripheral retina.
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Brodmann, K.: Vergleichende Lokalisationslehre der Groβhirnrinde, pp. 1–324. Leipzig: Barth 1909
Casagrande, V.A., Harting, J.K.: Transneuronal transport of tritiated fucose and proline in the visual pathways of tree shrew Tupaia glis. Brain Res. 96, 367–372 (1975)
Dräger, U.C.: Autoradiography of tritiated proline and fucose transported transneuronally from the eye to the visual cortex in pigmented and albino mice. Brain Res. 82, 284–292 (1974)
Florence, S. L., Casagrande, V. A.: A note on the evolution of ocular dominance columns in primates. Invest. Opthal. Vis. Sci., Suppl. (ARVO abstr.) 291–292 (1978)
Glendenning, K.K., Kofron, E.A., Diamond, I.T.: Laminar organization of projections of the lateral geniculate nucleus to the striate cortex in Galago. Brain Res. 105, 538–546 (1976)
Grafstein, B.: Transneuronal transfer of radioactivity in the central nervous system. Science 172, 177–179 (1971)
Grafstein, B., Laureno, R.: Transport of radioactivity from eye to visual cortex in the mouse. Exp. Neurol. 39, 44–57 (1973)
Graham, R.C., Karnovsky, M.J.: The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. J. Histochem. Cytochem. 14, 291–302 (1966)
Harting, J.K., Casagrande, V.A., Weber, J.T.: The projection of the primate superior colliculus upon the dorsal lateral geniculate nucleus: autoradiographic demonstration of interlaminar distribution of tectogeniculate axons. Brain Res. 150, 593–599 (1978)
Hassler, R., Wagner, A.: Experimentelle und morphologische Befunde über die vierfache corticale Projektion des visuellen Systems. 8. Int. Congress Neurol. 77–96 (1965)
Hendrickson, A.E., Wilson, J.R., Ogren, M.P.: The neuroanatomical organization of pathways between the dorsal lateral geniculate nucleus and visual cortex in Old World and New World primates. J. Comp. Neurol. 182, 123–136 (1978)
Hubel, D.H.: An autoradiographic study of the retino-cortical projections in the tree shrew (Tupaia glis). Brain Res. 96, 41–50 (1975)
Hubel, D.H., Wiesel, T.N.: Receptive fields and functional architecture of monkey striate cortex. J. Physiol. (Lond.) 195, 215–244 (1968)
Hubel, D.H., Wiesel, T.N.: Laminar and columnar distribution of geniculo-cortical fibers in the macaque monkey. J. Comp. Neurol. 146, 421–450 (1972)
Hubel, D.H., Wiesel, T.N.: Functional architecture of macaque monkey visual cortex. Proc. Roy. Soc. Lond. 198, 1–59 (1977)
Hubel, D.H., Wiesel, T.N., LeVay, S.: Columnar organization of area 17 in normal and monocularly deprived macaque monkeys. Exp. Brain Res. Suppl. 1, 356–361 (1976)
Hubel, D.H., Wiesel, T.N., LeVay, S.: Plasticity of ocular dominance columns in monkey striate cortex. Phil. Trans. Roy. Soc. Lond. B 278, 377–409 (1977)
Huérta, M.F., Casagrande, V.A., Weber, J.T., Harting, J.K.: Transneuronal transport of 3H-proline within the visual system. Neurosci. Abstr. 2, 1078 (1976)
Ito, M., Sanides, D., Creutzfeldt, O.D.: A study of binocular convergence in cat visual cortex neurons. Exp. Brain Res. 28, 21–35 (1977)
Kaas, J.H., Lin, C.S., Casagrande, V.A.: The relay of ipsilateral and contralateral retinal input from the lateral geniculate nucleus to striate cortex in the owl monkey: a transneuronal transport study. Brain Res. 106, 371–378 (1976)
Kennedy, C., des Rosiers, M.H., Sakurada, O., Shinohara, M., Reivich, M., Jehle, J.E., Sokoloff, L.: Metabolie mapping of primary visual system of monkey by means of autoradiographic (14C) deoxyglucose technique. Proc. Nat. Acad. Sci. Wash. 73, 4230–4234 (1976)
LeVay, S., Gilbert, C.D.: Laminar patterns of geniculocortical projections in the cat. Brain Res. 113, 1–19 (1976)
LeVay, S., Stryker, M.P., Shatz, C.J.: Ocular dominance columns and their development in layer IV of the cat's visual cortex: a quantitative study. J. Comp. Neurol. 179, 223–244 (1978)
Lund, J.S.: Organization of neurons in the visual cortex, area 17, of the monkey (Macaca mulatta). J. Comp. Neurol. 147, 455–496 (1973)
Malpeli, J.G., Baker, F.H.: The representation of the visual field in the lateral geniculate nucleus of Macaca mulatta. J. Comp. Neurol. 161, 569–594 (1975)
Ogren, M., Hendrickson, A.: Pathways between striate cortex and subcortical regions in Macaca mulatta and Saimiri sciureus: evidence for a reciprocal pulvinar connection. Exp. Neurol. 53, 780–800 (1976)
Norden, J.J., Kaas, J.H.: The identification of relay neurons in the dorsal lateral geniculate nucleus of monkeys using horseradish peroxidase. J. Comp. Neurol. 182, 707–726 (1978)
Rakic, P.: Prenatal development of the visual system in rhesus monkey. Phil. Trans. Roy. Soc. Lond. 278, 245–260 (1977)
Rowe, M.H., Rezak, M., Benevento, L.A.: Geniculate projections to striate cortex (area 17) in the squirrel monkey as demonstrated by transneuronal autoradiography. Neurosci. Abstr. 3, 575 (1977)
Shatz, C.J., Lindström, S., Wiesel, T.N.: The distribution of afferents representing the right and left eyes in the cat's visual cortex. Brain Res. 131, 103–116 (1977)
Spatz, W.B.: An efferent connection of the solitary cells of Meynert. A study with horseradish peroxidase in the marmoset Callithrix. Brain Res. 92, 450–455 (1975)
Spatz, W.B.: Topographically organized reciprocal connections between areas 17 and MT (visual area of superior temporal sulcus) in the marmoset Callithrix jacchus. Exp. Brain Res. 27, 559–572 (1977)
Spatz, W.B.: The retino-geniculo-cortical pathway in Callithrix. I. Intraspecific variations in the lamination pattern of the lateral geniculate nucleus. Exp. Brain Res. 33, 551–563 (1978)
Spatz, W.B., Tigges, J.: Species difference between Old World and New World monkeys in the organization of striate — prestriate association. Brain Res. 43, 591–594 (1972)
Spatz, W.B., Tigges, J., Tigges, M.: Subcortical projections, cortical associations, and some intrinsic interlaminar connections of the striate cortex in the squirrel monkey (Saimiri). J. Comp. Neurol. 140, 155–174 (1970)
Specht, S., Grafstein, B.: Accumulation of radioactive protein in mouse cerebral cortex after injection of 3H-fucose into the eye. Exp. Neurol. 41, 705–722 (1973)
Tigges, J., Tigges, M.: Ocular dominance columns in the striate cortex of chimpanzee (Pan troglodytes). Brain Res. (in press)
Tigges, J., Tigges, M., Perachio, A.A.: Complementary laminar terminations of afferents to area 17 originating in area 18 and in the lateral geniculate nucleus in squirrel monkey. J. Comp. Neurol. 176, 87–100 (1977)
Weber, J.T., Casagrande, V.A., Harting, J.K.: Transneuronal transport of 3H-proline within the visual system of the grey squirrel. Brain Res. 129, 346–352 (1977a)
Weber, J.T., Kaas, J.H., Huérta, M.F., Harting, J.K.: Connections of the lateral geniculate nucleus (LGN) of the squirrel monkey. Neurosci. Abstr. 3, 580 (1977b)
Wiesel, T.N., Hubel, D.H., Lam, D.M.K.: Autoradiographic demonstration of ocular-dominance columns in the monkey striate cortex by means of transneuronal transport. Brain Res. 79, 273–279 (1974)
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Spatz, W.B. The retino-geniculo-cortical pathway in Callithrix. II. The geniculo-cortical projection. Exp Brain Res 36, 401–410 (1979). https://doi.org/10.1007/BF00238512
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DOI: https://doi.org/10.1007/BF00238512