Abstract
Diabetes is a chronic progressive disease associated with different co-morbidities. The availability of insulin or effective use of insulin in the body is the major cause of this disease. Enhanced blood sugar or hyperglycemia is the manifestation of this disease. If not treated timely, diabetes can damage cardiac system, blood vessels, vision, renal function and nerves leading to increased risk of cardiac disease, stroke and may cause neuronal, retinal, and kidney disease. The overall risk of morbidity and mortality among diabetes affected people is more than double compared to non-diabetic people (WHO n.d.).
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References
Anjana RM et al (2011) Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: phase I results of the Indian Council of Medical Research-INdia DIABetes (ICMR-INDIAB) study. Diabetologia 54:3022
Anjana RM et al (2014) Physical activity and inactivity patterns in India – results from the ICMR-INDIAB study (Phase-1) [ICMR-INDIAB-5]. Int J Behav Nutr Phys Act 11:26
Anjana RM et al (2017) Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study. Lancet Diabetes Endocrinol 5(8):585–596. https://doi.org/10.1016/S2213-8587(17)30174-2. Erratum in: Lancet Diabetes Endocrinol. 2017;5(8): e5
ICMR (2012) Diet and nutritional status of rural population, prevalence of hypertension and diabetes among adults and infant and young child feeding practices – report of third repeat survey. National Institute of Nutrition, ICMR, Hyderabad
International Diabetes Federation (2015) IDF diabetes atlas, 7th edn. International Diabetes Federation, Brussels
Kaveeshwar SA, Cornwall J (2014) The current state of diabetes mellitus in India. Australas Med J 7:45–48
Khardori R et al (n.d.) Type 2 diabetes mellitus. https://emedicine.medscape.com/. Accessed 4 Mar 2019
Nielsen EM et al (2003) The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes. Diabetes 52(2):573–577
Radha V, Mohan V (2007) Genetic predisposition to type 2 diabetes among Asian Indians. Indian J Med Res 125(3):259–274
Ramachandran A (2005) Epidemiology of diabetes in India--three decades of research. J Assoc Physicians India 53:34–38
Sandhu MS et al (2007) Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 39(8):951–953
Saxena R et al (2010) Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 42(2):142–148
Sladek R et al (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445(7130):881–885
Tabassum R et al (2012) Common variants of IL6, LEPR, and PBEF1 are associated with obesity in Indian children. Diabetes 61:626–631
Tabassum R et al (2013) Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21. Diabetes 62:977–986
Tripathy JP et al (2017) Prevalence and risk factors of diabetes in a large community-based study in North India: results from a STEPS survey in Punjab, India. Diabetol Metab Syndr 9:8. https://doi.org/10.1186/s13098-017-0207-3
Ukkola O et al (2001) Insulin like growth factor 2 and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes. Diabetologia 44(12):2231–2236
Wheeler E, Barroso I (2011) Genome-wide association studies and type 2 diabetes. Brief Funct Genomics 10(2):52–60
WHO (2014) Global status report on non-communicable diseases 2014. World Health Organization, Geneva
WHO (2016) Global report on diabetes. WHO, Geneva
WHO (n.d.). http://www.who.int/mediacentre/factsheets/fs312/en/. Accessed 24 Mar 2016
Winckler W et al (2007) Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 56(3):685–693
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Misra, P., Chakrabarti, R. (2021). Introduction to Diabetes and Prevalence in India. In: Dikshit, M. (eds) Drug Discovery and Drug Development. Springer, Singapore. https://doi.org/10.1007/978-981-15-8002-4_6
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DOI: https://doi.org/10.1007/978-981-15-8002-4_6
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