Neoadjuvant and Adjuvant Therapy for Rectal Cancer

Parray, Fazl Q.; Baba, Arshad A.; Banday, Manzoor Ahmed; Shukla, Richa

doi:10.1007/978-981-13-7197-4_12

Fazl Q. Parray³,
Arshad A. Baba⁴,
Manzoor Ahmed Banday⁵ &
…
Richa Shukla⁵

436 Accesses

Abstract

The management of colorectal cancer has undergone a paradigm shift from previously proctectomy alone being standard of care to present-day multimodality treatment. The multimodality management involves the interplay between different specialty care providers in isolation or in combination, which often includes colorectal surgery, medical oncology, radiation oncology, Wound, ostomy, continence nursing (WOCN), radiology, pathology, pain and palliative care physician and genetics. The present multimodality treatment is aimed to increase the survival and reduce the recurrence and improve the quality of life.

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Abbreviations

ACOSOG:: American College of Surgeons Oncology Group institutions
EGFR:: Epidermal growth factor receptor
EORTC:: European Organisation for Research and Treatment of Cancer
FOLFOX:: 5-Fluorouracil, Leucovorin, and Oxaliplatin
FU:: Fluorouracil
Gy:: gray (symbol: Gy) is a derived unit of ionizing radiation dose in the International System of Units (SI)
IMPACT:: International Multicenter Pooled Analyses of Colon Cancer Trials
K-ras:: a gene that acts as an on/off switch in cell signaling
LV:: Leucovorin
MOSAIC:: Multicenter International Study of Oxaliplatin/5FU-LV in the Adjuvant Treatment of Colon Cancer
pCR:: pathologic complete response
SRCT:: Swedish Rectal Cancer Trial
TNM:: Tumor, Node, Metastasis

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Authors and Affiliations

Colorectal Division, Department of General Surgery, SKIMS, Srinagar, India
Fazl Q. Parray
Colorectal Division, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
Arshad A. Baba
Capitol Hospital, Jalandhar, Punjab, India
Manzoor Ahmed Banday & Richa Shukla

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Fazl Q. Parray
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Arshad A. Baba
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Manzoor Ahmed Banday
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Richa Shukla
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Editors and Affiliations

Colorectal Surgery, Sher-i-Kashmir Institute of Medical Sciences, Jammu and Kashmir, India
Fazl Q. Parray
Colorectal Surgery, Sher-i-Kashmir Institute of Medical Sciences, Jammu and Kashmir, India
Nisar Ahmad Chowdri

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Parray, F.Q., Baba, A.A., Banday, M.A., Shukla, R. (2020). Neoadjuvant and Adjuvant Therapy for Rectal Cancer. In: Parray, F., Chowdri, N. (eds) New Treatment Modalities in Rectal Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-13-7197-4_12

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DOI: https://doi.org/10.1007/978-981-13-7197-4_12
Published: 19 February 2020
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-7196-7
Online ISBN: 978-981-13-7197-4
eBook Packages: MedicineMedicine (R0)

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