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Cardiopulmonary and Gastrointestinal Manifestations of Patients with Ankylosing Spondylitis

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Surgical Treatment of Ankylosing Spondylitis Deformity
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Abstract

Many previous publications have reported that cardiac manifestations were involved in 2–10% of AS patients, such as aortitis, cardiomyopathy, conduction disorders, and valvular regurgitation, and were associated with AS. What is more, human leukocyte antigen (HLA)-B27 is found in most AS patients and is demonstrated to contribute to the pathophysiologic changes of the aforementioned conditions [1].

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References

  1. Moyssakis I, Gialafos E, Vassiliou VA, et al. Myocardial performance and aortic elasticity are impaired in patients with ankylosing spondylitis. Scand J Rheumatol. 2009;38(3):216–21.

    Article  CAS  PubMed  Google Scholar 

  2. Bulkley BH, Roberts WC. Ankylosing spondylitis and aortic regurgitation: description of the characteristic cardiovascular lesion from study of eight necropsy patients. Circulation. 1973;48(5):1014–27.

    Article  CAS  PubMed  Google Scholar 

  3. Roldan CA, Chavez J, Wiest PW, et al. Aortic root disease and valve disease associated with ankylosing spondylitis. J Am Coll Cardiol. 1998;32(5):1397–404.

    Article  CAS  PubMed  Google Scholar 

  4. Kaźmierczak J, Peregud-Pogorzelska M, Biernawska J, et al. Cardiac arrhythmias and conduction disturbances in patients with ankylosing spondylitis. Angiology. 2008;58(6):751–6.

    Article  Google Scholar 

  5. Toussirot E, Bahjaoui-Bouhaddi M, Poncet JC, et al. Abnormal autonomic cardiovascular control in ankylosing spondylitis. Ann Rheum Dis. 1999;58(8):481–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Fu J, Wu MY, Liang Y, et al. Differences in cardiovascular manifestations between ankylosing spondylitis patients with and without kyphosis. Clin Rheumatol. 2016;35(8):2003–8.

    Article  PubMed  Google Scholar 

  7. Fu J, Song K, Zhang YG, et al. Changes in cardiac function after pedicle subtraction osteotomy in patients with a kyphosis due to ankylosing spondylitis. Bone Joint J. 2015;97-B(10):1405–10.

    Article  CAS  PubMed  Google Scholar 

  8. Dunham C, Kautz F. Sondylarthritis ankylopoietica, a review and report of twenty cases. Am J Med Sci. 1941;201:232–50.

    Article  Google Scholar 

  9. Kanathur N, Lee-Chiong T. Pulmonary manifestations of ankylosing spondylitis. Clin Chest Med. 2010;31(3):547–54.

    Article  PubMed  Google Scholar 

  10. Davies D. Lung fibrosis in ankylosing spondylitis. Thorax. 1972;27(2):262.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Thai D, Ratani RS, Salama S, Steiner RM. Upper lobe fibrocavitary disease in a patient with back pain and stiffness. Chest. 2000;118(6):1814–6.

    Article  CAS  PubMed  Google Scholar 

  12. Baser S, Cubukcu S, Ozkurt S, et al. Pulmonary involvement starts in early stage ankylosing spondylitis. Scand J Rheumatol. 2006;35(4):325–7.

    Article  CAS  PubMed  Google Scholar 

  13. Casserly IP, Fenlon HM, Breatnach E, Sant SM. Lung findings on high-resolution computed tomography in idiopathic ankylosing spondylitis-correlation with clinical findings, pulmonary function testing and plain radiography. Br J Rheumatol. 1997;36(6):677–82.

    Article  CAS  PubMed  Google Scholar 

  14. Souza AS, Müller NL, Marchiori E, et al. Pulmonary abnormalities in ankylosing spondylitis: inspiratory and expiratory high-resolution CT findings in 17 patients. J Thorac Imaging. 2004;19(4):259–63.

    Article  PubMed  Google Scholar 

  15. Senocak O, Manisali M, Ozaksoy D, et al. Lung parenchyma changes in ankylosing spondylitis: demonstration with high resolution CT and correlation with disease duration. Eur J Radiol. 2003;45:117–22.

    Article  PubMed  Google Scholar 

  16. Zhang GY, Fu J, Zhang YG, et al. Lung volume change after pedicle subtraction osteotomy in patients with ankylosing spondylitis with thoracolumbar kyphosis. Spine (Phila Pa 1976). 2015;40(4):233–7.

    Article  CAS  Google Scholar 

  17. Fu J, Zhang GY, Zhang YG, et al. Pulmonary function improvement in patients with ankylosing spondylitis kyphosis following pedicle subtraction osteotomy. Spine (Phila Pa 1976). 2014;39(18):E1116–22.

    Article  Google Scholar 

  18. de Vlam K, Mielants H, Cuvelier C, et al. Spondyloarthropathy is underestimated in inflammatory bowel disease: prevalence and HLA association. J Rheumatol. 2000;27:2860–5.

    PubMed  Google Scholar 

  19. Brophy S, Pavy S, Lewis P, et al. Inflammatory eye, skin, and bowel disease in spondyloarthritis: genetic, phenotypic, and environmental factors. J Rheumatol. 2001;28:2667–73.

    CAS  PubMed  Google Scholar 

  20. Smale S, Natt RS, Orchard TR, et al. Inflammatory bowel disease and spondylarthropathy. Arthritis Rheum. 2001;44:2728–36.

    Article  CAS  PubMed  Google Scholar 

  21. Vaile JH, Meddings JB, Yacyshyn BR, et al. Bowel permeability and CD45RO expression on circulating CD20CB cells in patients with ankylosing spondylitis and their relatives. J Rheumatol. 1999;26:128–35.

    CAS  PubMed  Google Scholar 

  22. Liu C, Song K, Zhang YG, et al. Changes of the abdomen in patients with ankylosing spondylitis kyphosis. Spine. 2014;40:E43–8.

    Article  Google Scholar 

  23. Liu C, Zheng GQ, Zhang YG, et al. The radiologic, clinical results and digestive function improvement in patients with ankylosing spondylitis kyphosis after pedicle subtraction osteotomy. Spine J. 2015;15:1988–93.

    Article  PubMed  Google Scholar 

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Fu, J., Wang, Z. (2019). Cardiopulmonary and Gastrointestinal Manifestations of Patients with Ankylosing Spondylitis. In: Wang, Y. (eds) Surgical Treatment of Ankylosing Spondylitis Deformity . Springer, Singapore. https://doi.org/10.1007/978-981-13-6427-3_3

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  • DOI: https://doi.org/10.1007/978-981-13-6427-3_3

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  • Publisher Name: Springer, Singapore

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  • Online ISBN: 978-981-13-6427-3

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