Abstract
Continuous environmental monitoring and human health diagnostics are important tasks of modern science. We are developing multifunctional biosensor equipment for solving these problems. It is essential that the appropriate devices are multifunctional, highly sensitive and convenient for practical use in everyday life and industrial conditions. As an example, here we show the results of the development of highly sensitive new generation biosensors for the analysis of some xenobiotics in wastewater and functional health markers in human liquids. The recent results on the construction of laboratory prototypes of amperometric enzymatic biosensors in which we use the gold nanoparticles in combination with different polymers as a host matrix will be discussed. The results of using track polymer structures to create novel biosensors will be also presented. The developed ion track-based nanosensors provide high sensitivity, low power and low cost. They shall be modified further towards portable tools for in-situ chemical analysis in space and terrestrial applications. The generic track-based nanosensors platform is suitable for detection and analysis of gases and volatile organic compounds, specifically of biomolecules, in both gaseous and liquid phases.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Dmitruk K et al (2008) Construction of flavocytochrome b 2-overproducing strains of the thermotolerant methylotrophic yeast. Hansenula polymorpha (Pichia angusta). Microbiology 77:213
Bondaruk YU et al (2020) Simulation of the passage of ion flows through nanotracks. Intern J Adv Comp Techn 9:1
Smutok O et al (2017) Development of a new mediatorless biosensor based on flavocytochrome b 2immobilized onto gold nanolayer for non-invasive L-lactate analysis of human liquids. Sens Actuators B 250:469
Kavetskyy T et al (2017) Laccase-containing ureasil-polymer composite as the sensing layer of an amperometric biosensor. J Appl Polym Sci 134:45278
Kavetskyy T et al (2017) Network properties of ureasil-based polymer matrixes for construction of amperometric biosensors as probed by PALS and swelling experiments. Acta Phys Pol A 132:1515
Kavetskyy TS et al (2018) Ureasil-based polymer matrices as sensitive layers for the construction of amperometric biosensors. NATO SPS B Phys Biophys 30:309
Kavetskyy TS et al (2018) Swelling behavior of organic-inorganic ureasil-based polymers. NATO SPS B Phys Biophys 32:333
Ermakov V, Kruchinin S, Fujiwara A (2008) Electronic nanosensors based on nanotransistor with bistability behaviour. In: Bonca J, Kruchinin S (eds) Proceedings NATO ARW “Electron transport in nanosystems”. Springer, Dordrecht, pp 341–349
Ermakov V, Kruchinin S, Hori H, Fujiwara A (2007) Phenomena in the resonant tunneling through degenarate energy state with electron correlation. Int J Mod Phys B 11:827–835
Ermakov V, Kruchinin S, Pruschke T, Freericks J (2015) Thermoelectricity in tunneling nanostructures. Phys Rev B 92:115531
Kavetskyy T et al (2019) Improvement of amperometric laccase biosensor using enzyme-immobilized gold nanoparticles coupling with ureasil polymer as a host matrix. Gold Bull 52:79
Kavetskyy T et al (2019) Dependence of operational parameters of laccase-based biosensors on structure of photocross-linked polymers as holding matrixes. Eur Polym J 115:391
Kavetskyy T et al (2020) Controlling the network properties of polymer matrixes for improvement of amperometric enzyme biosensors: contribution of positron annihilation. Acta Phys Pol A 137:246
Fink D et al (2016) Nuclear track-based biosensing: an overview. Radiat Eff Defects Solids 171:173
Acar ET et al (2018) Concentration-polarization-induced precipitation and ionic current oscillations with tunable frequency. J Phys Chem C 122:3648
Fink D et al (2009) Glucose determination using a re-usable enzyme-modified ion track membrane. Biosens Bioelectron 24:2702
Acknowledgements
This work was financially supported in part by the Ministry of Education and Science of Ukraine (projects #0117U007143; to YK and KZ, #0118U000297 and #0119U100671; to TK, YK, OS, and MG), National Academy of Sciences of Ukraine in the frame of the Scientific-Technical Program “Smart sensor devices of a new generation based on modern materials and technologies” (project #13; to OS and MG), Slovak Grant Agency VEGA (project #2/0157/17; to OŠ), and Slovak Research and Development Agency (project #APVV-16-0369; to OŠ). TK, YK, and KZ also acknowledge the SAIA for scholarship in the IPSAS within the National Scholarship Programme of the Slovak Republic.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature B.V.
About this paper
Cite this paper
Kavetskyy, T. et al. (2020). Polymer Lattice and Track Nanostructures to Create Novel Biosensors. In: Bonča, J., Kruchinin, S. (eds) Advanced Nanomaterials for Detection of CBRN. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-2030-2_19
Download citation
DOI: https://doi.org/10.1007/978-94-024-2030-2_19
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-024-2029-6
Online ISBN: 978-94-024-2030-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)