Zusammenfassung
Mezlozillin ist ein Ureidopenizillin mit Wirkung gegen ein breites Spektrum grampositiver und gramnegativer Bakterien. Die Ausscheidung des organischen Anions Mezlozillin (pKa 3,5) erfolgt renal und biliär. Es wurde diskutiert, daß die beim Menschen beschriebene nichtlineare Kinetik mit dem Transport von Mezlozillin in der Leber in Zusammenhang steht [3]. Bei den vorliegenden Experimenten wurde der Mezlozillineinstrom in die Leber (zelluläre Aufnahme), also der sinusoidale Plasmamembrantransport in isolierten Rattenlebern untersucht.
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Gärtner, U. et al. (1984). Postersession VI. In: 90. Kongreß. Verhandlungen der Deutschen Gesellschaft für Innere Medizin, vol 90. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-85457-6_78
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DOI: https://doi.org/10.1007/978-3-642-85457-6_78
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