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Wilms Tumor

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Radiation Therapy in Pediatric Oncology

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Carefully designed, controlled clinical trials conducted by the National Wilms Tumor Study (NWTS) committee have refined the indications for adjuvant chemotherapy and radiotherapy in the management of Wilms tumor (WT) patients. Fewer patients now require radiotherapy and those that do, need a smaller dose than was historically given. At the same time, treatment outcome has improved. Reduction in therapy duration, intensity, and dose holds the promise of fewer late effects of decreased severity. Despite the reduced requirement for radiotherapy, the radiation oncologist remains an essential member of the management team. The purpose of this chapter is to review the clinical science that the radiation oncologist will require in the current management of patients with WT.

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Authors and Affiliations

  1. Division of Radiation Oncology, Johns Hopkins Oncology Center, 600 N. Wolfe Street, Baltimore, MD, 21287, USA

    Moody D. Wharam Jr. M.D. (Professor)

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  1. Moody D. Wharam Jr. M.D.
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Editors and Affiliations

  1. Department of Radiation Oncology, College of Medicine, The University Arizona, Health Science Center, 1501 North Campbell Ave., 85724, Tucson, AZ, USA

    J. Robert Cassady M.D. (Professor) (Professor)

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© 1994 Springer-Verlag Berlin Heidelberg

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Wharam, M.D. (1994). Wilms Tumor. In: Cassady, J.R. (eds) Radiation Therapy in Pediatric Oncology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84520-8_17

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  • DOI: https://doi.org/10.1007/978-3-642-84520-8_17

  • Publisher Name: Springer, Berlin, Heidelberg

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