Abstract
Asbestos fibers belong to a family of ubiquitous mineral silicates. Two types of malignancies have been documented in respiratory tract and pleura following inhalation of asbestos. Bronchogenic carcinoma, arising in the tracheobronchialepithelium, is a tumor found in individuals exposed occupationally to asbestos. Since this tumor is rarely found in non-smoking asbestos workers, asbestos is thought to act mainly as a co-carcinogen or tumor promoter in the development of this disease (Mossman et al. 1990). However, the development of malignant mesothelioma in the pleura is not associated with cigarette smoking. The generally accepted view is that amphibole asbestos acts as a complete carcinogen in the development of mesothelioma (Mossman et al.1990).
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© 1994 Springer-Verlag Berlin Heidelberg
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Janssen, Y. et al. (1994). Activation of Early Cellular Responses by Asbestos: Induction of c-FOS and c-JUN Protooncogene Expression in Rat Pleural Mesothelial Cells. In: Davis, J.M.G., Jaurand, MC. (eds) Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres. NATO ASI Series, vol 85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79041-6_18
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DOI: https://doi.org/10.1007/978-3-642-79041-6_18
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