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Chronic Gastritis and Nonulcer Dyspepsia

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Gastroduodenal Disease and Helicobacter pylori

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 241))

Abstract

The relationship between Helicobacter pylori gastritis and non-ulcer dyspepsia (NUD; operationally defined as chronic or recurrent pain or discomfort centred in the upper abdomen in the absence of peptic ulceration) has remained in contention for many years. Recently, increasing data have accumulated that support the null hypothesis that there is no true relationship between H. pylori infection and NUD, although there remains healthy scepticism in the scientific community. In this chapter, the epidemiological and pathophysiological data linking gastritis and dyspepsia are reviewed, and the clinical trial evidence is then summarized.

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  1. Department of Medicine, University of Sydney, Nepean Hospital, PO Box 63, Penrith, NSW, 2751, Australia

    J. Kalantar, G. D. Eslick & N. J. Talley

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  2. G. D. Eslick
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  3. N. J. Talley
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Editors and Affiliations

  1. Medical Service (111), Central Texas Veterans Health Care System, Texas A&M University, College of Medicine, 1901 S. First Street, Temple, TX, 76504, USA

    T. Ulf Westblom M.D. (Chief) (Chief)

  2. Department of Pediatrics, Division of Pediatric Gastroenterology, Rainbow Babies and Children Hospital, Case Western Reserve University, 2074 Abington Road, Cleveland, OH, 44106, USA

    Steven J. Czinn M.D.

  3. Institute of Pathology, Case Western Reserve University, Biomedical Research Building, Rm. 919, 10900 Euclid Avenue, Cleveland, OH, 44106-4943, USA

    John G. Nedrud Ph.D. (Associate Professor) (Associate Professor)

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Kalantar, J., Eslick, G.D., Talley, N.J. (1999). Chronic Gastritis and Nonulcer Dyspepsia. In: Westblom, T.U., Czinn, S.J., Nedrud, J.G. (eds) Gastroduodenal Disease and Helicobacter pylori . Current Topics in Microbiology and Immunology, vol 241. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60013-5_3

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