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Breast Cancer

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Hypofractionated and Stereotactic Radiation Therapy

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Abstract

The benefit of post-lumpectomy and postmastectomy RT in improving local control and overall survival has been demonstrated through multiple randomized trials. The conventional fractionation scheme has evolved to be 25 RT treatments (2 Gy/fraction) to the whole breast with an additional RT boost to the lumpectomy cavity or mastectomy scar. However, multiple randomized studies have subsequently explored hypofractionated whole breast RT in specific populations. Another approach, APBI, has been explored in the post-lumpectomy setting to target only the lumpectomy cavity. These alternative approaches to conventional whole breast RT are viable options in certain patient populations.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Kevin Pearlstein & Ellen Jones

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  1. Kevin Pearlstein
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  2. Ellen Jones
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Correspondence to Ellen Jones .

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Editors and Affiliations

  1. Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA

    Orit Kaidar-Person

  2. Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina, USA

    Ronald Chen

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Pearlstein, K., Jones, E. (2018). Breast Cancer. In: Kaidar-Person, O., Chen, R. (eds) Hypofractionated and Stereotactic Radiation Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-92802-9_19

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  • DOI: https://doi.org/10.1007/978-3-319-92802-9_19

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92800-5

  • Online ISBN: 978-3-319-92802-9

  • eBook Packages: MedicineMedicine (R0)

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