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Epidemiology and Natural History of Fibrostenosing Inflammatory Bowel Disease

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Fibrostenotic Inflammatory Bowel Disease

Abstract

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, relapsing inflammatory gastrointestinal diseases. CD frequently results in transmural inflammation and is more commonly associated with stricturing diseases compared with UC. Inflammation in UC is usually only limited to the mucosa and stricture formation in the colon occurs rarely. Strictures in IBD can be secondary to either inflammation or fibrosis and it is important to determine the aetiology to provide definitive treatment. Once strictures occur, they can be challenging to manage. Despite the advent of multiple new therapeutic agents for IBD, there has been no significant impact on the incidence and morbidity of strictures.

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Author information

Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore, Singapore

    Wee Khoon Ng

  2. Department of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Diseases, LKS Institute of Health Science, Chinese University of Hong Kong, Hong Kong, China

    Siew C. Ng

Authors
  1. Wee Khoon Ng
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  2. Siew C. Ng
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Correspondence to Siew C. Ng .

Editor information

Editors and Affiliations

  1. Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, USA

    Florian Rieder

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Ng, W.K., Ng, S.C. (2018). Epidemiology and Natural History of Fibrostenosing Inflammatory Bowel Disease. In: Rieder, F. (eds) Fibrostenotic Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-90578-5_2

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  • DOI: https://doi.org/10.1007/978-3-319-90578-5_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90577-8

  • Online ISBN: 978-3-319-90578-5

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