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Spinal Cord Stimulation for Chronic Abdominal Pain

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Advanced Procedures for Pain Management

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Abstract

Abdominal pain prompts about 16 million visits a year to primary care offices in the United States and is a major source of morbidity, lost productivity, and healthcare costs. About two million patients continue on to visit a specialist, usually a gastroenterologist [1]. Chronic abdominal pain of visceral origin can be difficult to treat. Over the past few years, spinal cord stimulation (SCS) has emerged as a potential therapy for those patients who are refractory to medical therapies and less invasive interventional therapies.

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References

  1. Peery AF, Dellon ES, Lund J, Crockett SD, McGowan CE, Bulsiewicz WJ, et al. Burden of gastrointestinal disease in the United States: 2012 update. Gastroenterology. 2012;143:1179–87.e1–3.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Greenwood-Van Meerveld B, Johnson AC, Foreman RD, Linderoth B. Attenuation by spinal cord stimulation of a nociceptive reflex generated by colorectal distention in a rat model. Auton Neurosci. 2003;104:17–24.

    Article  PubMed  Google Scholar 

  3. Kapural L, Narouze SN, Janicki TI, Mekhail N. Spinal cord stimulation is an effective treatment for the chronic intractable visceral pelvic pain. Pain Med. 2006;7:440–3.

    Article  PubMed  Google Scholar 

  4. Krames ES, Foreman R. Spinal cord stimulation modulates visceral nociception and hyperalgesia via the spinothalamic tracts and the postsynaptic dorsal column pathways: a literature review and hypothesis. Neuromodulation. 2007;10:224–37.

    Article  PubMed  Google Scholar 

  5. Linderoth B, Stiller CO, Gunasekera L, O’Connor WT, Ungerstedt U, Brodin E. Gamma-aminobutyric acid is released in the dorsal horn by electrical spinal cord stimulation: an in vivo microdialysis study in the rat. Neurosurgery. 1994;34:484–8; discussion 488–9.

    Article  CAS  PubMed  Google Scholar 

  6. Palecek J. The role of dorsal columns pathway in visceral pain. Physiol Res. 2004;53(Suppl 1):S125–30.

    PubMed  Google Scholar 

  7. Palecek J, Willis WD. The dorsal column pathway facilitates visceromotor responses to colorectal distention after colon inflammation in rats. Pain. 2003;104:501–7.

    Article  CAS  PubMed  Google Scholar 

  8. Qin C, Lehew RT, Khan KA, Wienecke GM, Foreman RD. Spinal cord stimulation modulates intraspinal colorectal visceroreceptive transmission in rats. Neurosci Res. 2007;58:58–66.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Linderoth B. Mechanisms of spinal cord stimulation in painful syndromes: role of animal models. Pain Med. 2006;34:484–8.

    Google Scholar 

  10. Linderoth B. Spinal cord stimulation: mechanisms of action. In: Burchiel K, editor. Surgical management of pain. New York: Thieme Medical; 2002.

    Google Scholar 

  11. Cui JG, O’Connor WT, Ungerstedt U, Linderoth B, Meyerson BA. Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic mechanism. Pain. 1997;73:87–95.

    Article  CAS  PubMed  Google Scholar 

  12. Kapural L. Spinal cord stimulation for visceral abdominal pain. In: Hayek SM, Levy R, Deer T, editors. Neurostimulation for the treatment of chronic pain, vol. 1. Philadelphia: Elsevier; 2011. p. 113–7.

    Google Scholar 

  13. Kapural L, Deer T, Yakovlev A, Bensitel T, Hayek S, Pyles S, et al. Technical aspects of spinal cord stimulation for managing chronic visceral abdominal pain: the results from the national survey. Pain Med. 2010;11:685–91.

    Article  PubMed  Google Scholar 

  14. Kapural L, Nagem H, Tlucek H, Sessler DI. Spinal cord stimulation for chronic visceral abdominal pain. Pain Med. 2010;11:347–55.

    Article  PubMed  Google Scholar 

  15. Kapural L, Cywinski JB, Sparks DA. Spinal cord stimulation for visceral pain from chronic pancreatitis. Neuromodulation. 2011;14:423–6; discussion 426–7.

    Article  PubMed  Google Scholar 

  16. Khan YN, Raza SS, Khan EA. Application of spinal cord stimulation for the treatment of abdominal visceral pain syndromes: case reports. Neuromodulation. 2005;8:14–27.

    Article  PubMed  Google Scholar 

  17. Kapur S, Mutagi H, Raphael J. Spinal cord stimulation for relief of abdominal pain in two patients with familial Mediterranean fever. Br J Anaesth. 2006;97:866–8.

    Article  CAS  PubMed  Google Scholar 

  18. Tiede JM, Ghazi SM, Lamer TJ, Obray JB. The use of spinal cord stimulation in refractory abdominal visceral pain: case reports and literature review. Pain Pract. 2006;6:197–202.

    Article  PubMed  Google Scholar 

  19. Kapural L, Rakic M. Spinal cord stimulation for chronic visceral pain secondary to chronic non-alcoholic pancreatitis. J Clin Gastroenterol. 2008;42:750–1.

    Article  PubMed  Google Scholar 

  20. Kim JK, Hong SH, Kim MH, Lee JK. Spinal cord stimulation for intractable visceral pain due to chronic pancreatitis. J Korean Neurosurg Soc. 2009;46:165–7.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Al-Mahrouqi H, Munro Z, Acland RH, MacFarlane MR. Spinal cord stimulation for intractable chronic upper abdominal pain: a case report of the first patient in New Zealand. N Z Med J. 2012;125:132–4.

    PubMed  Google Scholar 

  22. Ceballos A, Cabezudo L, Bovaira M, Fenollosa P, Moro B. Spinal cord stimulation: a possible therapeutic alternative for chronic mesenteric ischaemia. Pain. 2000;87:99–101.

    Article  CAS  PubMed  Google Scholar 

  23. Caruso C, Lo Sapio D, Ragosa V, Lo Sapio S, Cafora C, Romano L. Abdominal angina due to obstruction of mesenteric artery treated with spinal cord stimulation: a clinical case. Neuromodulation. 2011;14:146–9; discussion 149–50.

    Article  PubMed  Google Scholar 

  24. Krames E, Mousad DG. Spinal cord stimulation reverses pain and diarrheal episodes of irritable bowel syndrome: a case report. Neuromodulation. 2004;7:82–8.

    Article  PubMed  Google Scholar 

  25. Rana MV, Knezevic NN. Tripolar spinal cord stimulation for the treatment of abdominal pain associated with irritable bowel syndrome. Neuromodulation. 2013;16:73–7; discussion 77.

    Article  PubMed  Google Scholar 

  26. Lind G, Winter J, Linderoth B, Hellstrom PM. Therapeutic value of spinal cord stimulation in irritable bowel syndrome: a randomized crossover pilot study. Am J Physiol Regul Integr Comp Physiol. 2015;308:R887–94.

    Article  CAS  PubMed  Google Scholar 

  27. Jackson M, Simpson KH. Spinal cord stimulation in a patient with persistent oesophageal pain. Pain. 2004;112:406–8.

    Article  PubMed  Google Scholar 

  28. Kim CH, Issa M. Spinal cord stimulation for the treatment of chronic renal pain secondary to uretero-pelvic junction obstruction. Pain Physician. 2011;14:55–9.

    PubMed  Google Scholar 

  29. Yakovlev AE, Resch BE. Treatment of intractable abdominal pain patient with Bannayan-Riley-Ruvalcaba syndrome using spinal cord stimulation. WMJ. 2009;108:323–6.

    PubMed  Google Scholar 

  30. Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Thomson S, et al. The appropriate use of neurostimulation: avoidance and treatment of complications of neurostimulation therapies for the treatment of chronic pain. Neuromodulation Appropriateness Consensus Committee. Neuromodulation. 2014;17:571–97; discussion 597–8.

    Article  PubMed  Google Scholar 

  31. Conwell DL, Vargo JJ, Zuccaro G, Dews TE, Mekhail N, Scheman J, et al. Role of differential neuroaxial blockade in the evaluation and management of pain in chronic pancreatitis. Am J Gastroenterol. 2001;96:431–6.

    Article  CAS  PubMed  Google Scholar 

  32. Garcea G, Thomasset S, Berry DP, Tordoff S. Percutaneous splanchnic nerve radiofrequency ablation for chronic abdominal pain. ANZ J Surg. 2005;75:640–4.

    Article  PubMed  Google Scholar 

  33. Raj PP, Sahinler B, Lowe M. Radiofrequency lesioning of splanchnic nerves. Pain Pract. 2002;2:241–7.

    Article  PubMed  Google Scholar 

  34. Kapural L. Spinal cord stimulation for chronic abdominal pain. In: Kapural L, editor. Chronic abdominal pain: an evidence-based comprehensive guide to clinical management. New York: Springer; 2015. p. 195–200.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, Duke University, Durham, NC, USA

    Arun Ganesh

  2. Wake Forest School of Medicine, Carolinas Pain Institute, Winston-Salem, NC, USA

    Leonardo Kapural

Authors
  1. Arun Ganesh
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  2. Leonardo Kapural
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Correspondence to Leonardo Kapural .

Editor information

Editors and Affiliations

  1. Lenox Hill Hospital, New York, New York, USA

    Sudhir Diwan

  2. The Center for Pain Relief, Charleston, West Virginia, USA

    Timothy R Deer

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Ganesh, A., Kapural, L. (2018). Spinal Cord Stimulation for Chronic Abdominal Pain. In: Diwan, S., Deer, T. (eds) Advanced Procedures for Pain Management. Springer, Cham. https://doi.org/10.1007/978-3-319-68841-1_19

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  • DOI: https://doi.org/10.1007/978-3-319-68841-1_19

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-68839-8

  • Online ISBN: 978-3-319-68841-1

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