Abstract
The total skin-sparing mastectomy has become routinely offered to patients in our practice as the mastectomy has evolved from the radical, to modified radical, to simple mastectomy, then skin-sparing, and now total skin-sparing or nipple skin-sparing mastectomy. The current literature suggests that the total skin-sparing mastectomy is an oncologically safe procedure for patients, excluding those with involvement of the nipple-areola complex and those with skin involvement or inflammatory breast cancer. Throughout our experience with the total skin-sparing mastectomy, our techniques and inclusion criteria for the procedure have evolved as more data has become available.
We begin with our pre-incision injections for routine performance of the axillary reverse mapping procedure. This technique is used for sentinel lymph node biopsies as well as axillary lymph node dissections to minimize lymphedema of the ipsilateral upper extremity. Although our initial experience with the total skin-sparing mastectomy was mostly via an inframammary incision, we have transitioned to the vertical infra-areolar approach to the nipple-sparing mastectomy in most cases. This incision provides maximal preservation of the blood supply to the nipple and creates a superior cosmetic outcome to most other incisions as it sets the nipples in correct and matching position. However, we do recognize that there are exceptions, and we do utilize various other incisions when necessary.
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References
Bland C, et al. The breast: comprehensive management of benign and malignant diseases. Philadelphia, PA: Saunders Elsevier; 2009.
Vijayashree M, Chamberlain RS. Nipple-sparing mastectomy in modern breast practice. Clin Anat. 2013;26:56–65.
Fisher B, Anderson S, Bryant J, et al. Twenty year follow up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;1233–1241.
Krag DN, Anderson SJ, Julian TB, Brown AM, Harlow SP, et al. Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial. Lancet. 2010;11:927–33.
Hartman L, Schaid DJ, Woods JE, et al. Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. Engl J Med. 1999;340(2):77–84.
Gerber B, Krause A, Reimer T, et al. Skin-sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction is an oncologically safe procedure. Ann Surg. 2003;238:120–7.
Petit JY, Veronesi U, Rey P, et al. Nipple-sparing mastectomy: risk of nipple-areolar recurrences in a series of 579 cases. Breast Cancer Res Treat. 2009;97–101.
Petit JY, Veronesi U, Oreccchia P, et al. Nipple sparing mastectomy with nipple areola intraoperative radiotherapy: one thousand and one cases of a five years experience at the European Institute of Oncology of Milan (EIO). Breast Cancer Res Treat. 2009;117:333–8.
Margulies AG, Hochberg J, Kepple J, et al. Total skin sparing mastectomy without preservation of the nipple-areola complex. Am J Surg. 2005;190:920–6.
Sufi P, Gittos M, Collier D. Envelope mastectomy with immediate reconstruction (EMIR). Eur J Surg Oncol. 2000;26:367–70.
Crowe JP. Nipple-sparing mastectomy: technique and results of 54 procedures. JAMA Surg. 2004;148–150.
Wellisch DK, Schain WS, Noone RB, et al. The psychological contribution of nipple addition in breast reconstruction. Plast Reconstr Surg. 1987;699–704.
Didier F, Radice D, Gandini S, et al. Does nipple preservation in mastectomy improve satisfaction with cosmetic results, psychological adjustment, body image and sexuality? Breast Cancer Res Treat. 2009;623–633.
Piper M, Peled A, Foster R, et al. Total skin-sparing mastectomy, a systematic review of oncologic outcomes and postoperative complications. Ann Plast Surg. 2013;70(4):435–7.
Stolier AJ, Wang J. Terminal duct lobular units are scarce in the nipple: implications for prophylactic nipple-sparing mastectomy. Ann Surg Oncol. 2008;15(2):438–42.
Benediktsson KP, Perbeck L. Survival in breast cancer after nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants: a prospective trial with 13 years median follow up in 216 patients. Eur J Surg Oncol. 2007;34:143–8.
Huang NS. Nipple-sparing mastecotmy in breast cancer: from an oncologic safety perspective. Chin Med J (Engl). 2015;128(16):2256–61.
Stolier AJ, Sullivan SK, Dellacroce FJ. Technical considerations in nipple-sparing mastectomy: 82 consecutive cases without necrosis. Ann Surg Oncol. 2008;15(5):1341–7.
Rusby JE, Brachtel EF, Taghian A, et al. Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy. Am J Surg. 2007;194:433–7.
Burdge EC, Yuen J, Hardee M, et al. Nipple skin-sparing mastectomy is feasible for advanced disease. Ann Surg Oncol. 2013;20:3294–302. doi:10.1245/s10434-013-3174-4.
Boneti C, Yuen J, Santiago C, et al. Oncologic safety of nipple skin-sparing or total skin-sparing mastectomies with immediate reconstruction. J Am Coll Surg. 2011;212:686–93.
Klimberg VS, Rubio I, Henry R, et al. Intraoperative versus peritumoral injection for location of the sentnel node. Ann Surg. 1999;229(6):860–5.
Johnson CB, Boneti C, Korourian S, et al. Intraoperative injection of subareolar or dermal radioisotope results in predicatable identification of sentinel lymph nodes in breast cancer. Ann Surg. 2011;254(4):612–8.
Ochoa D, Korourian S, Boneti C, et al. Axillary reverse mapping: five-year experience. Surgery. 2014;1261–1268.
Boneti C, Korourian S, Diaz Z, et al. Axillary reverse mapping (ARM) to identify and protect lymphatics draining the arm during axillary lymphadenectomy. Am J Surg. 2009.
Kiluk JV, Santillan AA, Kaur P, et al. Feasibility of sentinel lymph node biopsy through an inframammary incision for a nipple-sparing mastectomy. Ann Surg Oncol. 2008;3402–3406.
Wapnir I, Dua M, Kieryn A, et al. Intraoperative imaging of nipple perfusion patterns and ischemic complications in nipple-sparing mastectomies. Ann Surg Oncol. 2014;21:100–6.
Layeeque R, Hochberg J, Siegel E, et al. Botulinum toxin infiltration for pain control after mastectomy and expander reconstruction. Ann Surg. 2004;240(4):608–13.
Colwell AS. Direct-to-implant breast reconstruction. Gland Surg [Online]. 2012;1.3:139–41.
Singh N, Reaven NL, Funk SE. Immediate 1-stage vs. tissue expander postmastectomy implant breast reconstructions: a retrospective real-world comparison over 18 months. J Plast Reconstr Aesthet Surg. 2012;65(7):917–23.
Munhoz AM, Montag E, Filassi JR, Gemperli R. Immediate nipple-areola-sparing mastectomy reconstruction: an update on oncological and reconstruction techniques. World J Clin Oncol. 2014;5(3):478–94.
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Rivere, A., Kumbla, P.A., Klimberg, V.S. (2017). The Vertical Infra-Areolar Approach to Nipple Skin-Sparing or Total Skin-Sparing Mastectomy. In: Harness, J., Willey, S. (eds) Operative Approaches to Nipple-Sparing Mastectomy. Springer, Cham. https://doi.org/10.1007/978-3-319-43259-5_6
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DOI: https://doi.org/10.1007/978-3-319-43259-5_6
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