Abstract
Splenic artery embolization is a safe and effective alternative to surgical splenectomy, especially in patients who are poor surgical candidates due to associated co-morbidities.
It is an especially useful for the treatment of variceal bleeding due to hepatic cirrhosis. Splenic trauma can also be treated by embolization of the splenic artery. This treatment modality is especially useful where selective embolization is needed as when pseudoaneurysms of the splenic artery. These can be selectively embolized which enables tissue preservation without the need for splenectomy.
In clinical situations where hypersplenism prevents use of anti platelets for concomitant percutaneous coronary revascularization, splenic artery embolization is a safe alternative to surgical splenectomy prior to coronary revascularization, as in this scenario, a high grade coronary stenosis would be a relative contra-indication for surgical splenectomy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Kadir S, Lundell C, Saeed M. Celiac, superior and inferior mesenteric arteries. In: Kadir S, editor. Atlas of normal and variant angiographic anatomy. Philadelphia: Saunders; 1991. p. 204–37.
Cullingford GL, Watkins DN, Watts AD, Mallon DF. Severe late postsplenectomy infection. Br J Surg. 1991;78:716–21.
Velmahos GC, Toutouzas KG, Radin R, Chan L, Demetriades D. Nonoperative treatment of blunt injury to solid abdominal organs. Arch Surg. 2003;138:844–51.
Albrecht RM, Schermer CR, Morris A. Nonoperative management of blunt splenic injuries: factors influencing success in age _55 years. Am Surg. 2002;68:227–30.
Sclafani SJ, Shaftan GW, Scalea TM, et al. Nonoperative salvage of computed tomography-diagnosed splenic injuries: utilization of angiography for triage and embolization for hemostasis. J Trauma. 1995;39:818–25.
Link DP, Seibert JA, Gould J, Lantz BM. On-line monitoring of sequential blood flow reduction during splenic embolization. Acta Radiol. 1989;30:101–3.
Levy JM, Wasserman PI, Weiland DE. Nonsuppurative gas formation in the spleen after transcatheter splenic infarction. Radiology. 1981;139:375–6.
Killeen KL, Shanmuganathan K, Boyd-Kranis R, Scalea TM, Mirvis SE. CT findings after embolization for blunt splenic trauma. J Vasc Interv Radiol. 2001;12:209–14.
Haan J, Bochicchio G, Kramer M, Scalea T. Air following splenic embolization: infection or incidental finding? Am Surg. 2003;69:1036–9.
Haan JM, Biffl W, Knudson MM, et al. Splenic embolization revisited: a multicenter review. J Trauma. 2004;56:542–7.
Kramer M, Scalea TM. Admission angiography for blunt splenic injury: advantages and pitfalls. J Trauma. 2001;51:1161–5.
Bessoud B, Denys A. Main splenic artery embolization using coils in blunt splenic injuries: effects on the intrasplenic blood pressure. Eur Radiol. 2004;14:1718–9.
Peck-Radosavljevic M. Hypersplenism. Eur J Gastroenterol Hepatol. 2001;13:317–23.
Sangro B, Bilbao I, Herrero I, et al. Partial splenic embolization for the treatment of hypersplenism in cirrhosis. Hepatology. 1993;18:309–14.
Romano M, Giojelli A, Capuano G, Pomponi D, Salvatore M. Partial splenic embolization in patients with idiopathic portal hypertension. Eur J Radiol. 2004;49:268–73.
Stanley P, Chen TC. Partial embolization of the spleen in patients with thalassemia. J Vasc Interv Radiol. 1995;6:137–42.
Kimura F, Ito H, Shimizu H, et al. Partial splenic embolization for the treatment of hereditary spherocytosis. AJR Am J Roentgenol. 2003;181:1021–4.
Kumar S, Diehn FE, Gertz MA, Tefferi A. Splenectomy for immune thrombocytopenic purpura: long-term results and treatment of postsplenectomy relapses. Ann Hematol. 2002;81:312–9.
Miyazaki M, Itoh H, Kaiho T, et al. Partial splenic embolization for the treatment of chronic idiopathic thrombocytopenic purpura. AJR Am J Roentgenol. 1994;163:123–6.
Athale UH, Kaste SC, Bodner SM, Ribeiro RC. Splenic rupture in children with hematologic malignancies. Cancer. 2000;88:480–90.
Gardner RV, Warrier RP, Loe W, Ward K, Haymon M, Craver R. Splenic artery embolization as emergency treatment of splenic rupture in a child with T-cell acute lymphocytic leukemia having t(8;14) translocation. Med Pediatr Oncol. 2003;41:492–3.
Pringle KC, Spigos DG, Tan WS, et al. Partial splenic embolization in the management of thalassemia major. J Pediatr Surg. 1982;17:884–91.
Jonasson O, Spigos DG, Mozes MF. Partial splenic embolization: experience in 136 patients. World J Surg. 1985;9:461–7.
Poulin EC, Mamazza J, Schlachta CM. Splenic artery embolization before laparoscopic splenectomy: an update. Surg Endosc. 1998;12:870–5.
Iwase K, Higaki J, Mikata S, et al. Laparoscopically assisted splenectomy following preoperative splenic artery embolization using contour emboli for myelofibrosis with massive splenomegaly. Surg Laparosc Endosc Percutan Tech. 1999;9:197–202.
Mozes MF, Spigos DG, Pollak R, et al. Partial splenic embolization, an alternative to splenectomy: results of a prospective, randomized study. Surgery. 1984;96:694–702.
Kumpe DA, Rumack CM, Pretorius DH, Stoecker TJ, Stellin GP. Partial splenic embolization in children with hypersplenism. Radiology. 1985;155:357–62.
Fukuda T, Yoshikawa T. Interventional radiologic treatment for idiopathic portal hypertension. Cardiovasc Intervent Radiol. 1999;22:311–4.
Shimizu T, Onda M, Tajiri T, et al. Bleeding portal- hypertensive gastropathy managed successfully by partial splenic embolization. Hepatogastroenterology. 2002;49:947–9.
Sato T, Yamazaki K, Toyota J, Karino Y, Ohmura T, Suga T. Gastric varices with splenic vein occlusion treated by splenic arterial embolization. J Gastroenterol. 2000;35:290–5.
Xu RY, Liu B, Lin N. Therapeutic effects of endoscopic variceal ligation combined with partial splenic embolization for portal hypertension. World J Gastroenterol. 2004;10:1072–4.
Taniai N, Onda M, Tajiri T, Toba M, Yoshida H. Endoscopic variceal ligation (EVL) combined with partial splenic embolization (PSE). Hepatogastroenterology. 1999;46:2849–53.
Chikamori F, Kuniyoshi N, Kawashima T, Shibuya S, Takase Y. Combination treatment of partial splenic embolization, endoscopic embolization and transjugular retrograde obliteration for complicated gastroesophageal varices. Hepatogastroenterology. 2004;51:1506–9.
Palsson B, Hallen M, Forsberg AM, Alwmark A. Partial splenic embolization: long-term outcome. Langenbecks Arch Surg. 2003;387:421–6.
McDermott VG, Shlansky-Goldberg R, Cope C. Endovascular management of splenic artery aneurysms and pseudoaneurysms. Cardiovasc Intervent Radiol. 1994;17:179–84.
Guillon R, Garcier JM, Abergel A, et al. Management of splenic artery aneurysms and false aneurysms with endovascular treatment in 12 patients. Cardiovasc Intervent Radiol. 2003;26:256–60.
Arepally A, Dagli M, Hofmann LV, Kim HS, Cooper M, Klein A. Treatment of splenic artery aneurysm with use of a stent-graft. J Vasc Interv Radiol. 2002;13:631–3.
Brountzos EN, Vagenas K, Apostolopoulou SC, Panagiotou I, Lymberopoulou D, Kelekis DA. Pancreatitis-associated splenic artery pseudoaneurysm: endovascular treatment with self-expandable stent-grafts. Cardiovasc Intervent Radiol. 2003;26:88–91.
De Carlis L, Sansalone CV, Rondinara GF, et al. Splenic artery steal syndrome after orthotopic liver transplantation: diagnosis and treatment. Transplant Proc. 1993;25:2594–6.
Uflacker R, Selby JB, Chavin K, Rogers J, Baliga P. Transcatheter splenic artery occlusion for treatment of splenic artery steal syndrome after orthotopic liver transplantation. Cardiovasc Intervent Radiol. 2002;25:300–6.
Galbraith PR. The mechanism of action of splenic irradiation in chronic myelogenous leukemia. Can Med Assoc J. 1967;96:1636–41.
Abrams RA, Liu PJ, Ambinder RF, et al. Hodgkin and non-Hodgkin lymphoma: local-regional radiation therapy after bone marrow transplantation. Radiology. 1997;203:865–70.
Elliott MA, Chen MG, Silverstein MN, Tefferi A. Splenic irradiation for symptomatic splenomegaly associated with myelofibrosis with myeloid metaplasia. Br J Haematol. 1998;103:505–11.
Schratter-Sehn AU, Cerveny M, Simmel H, Schlogl E, Schratter A. Short-time splenic irradiation for splenomegaly. Onkologie. 2003;26:21–4.
McFarland JT, Kuzma C, Millard FE, Johnstone PA. Palliative irradiation of the spleen. Am J Clin Oncol. 2003;26:178–83.
Herba MJ, Thirlwell MP. Radioembolization for hepatic metastases. Semin Oncol. 2002;29:152–9.
Salem R, Lewandowski R, Roberts C, et al. Use of yttrium-90 glass microspheres (TheraSphere) for the treatment of unresectable hepatocellular carcinoma in patients with portal vein thrombosis. J Vasc Interv Radiol. 2004;15:335–45.
Salem R, Thurston KG, Carr BI, Goin JE, Geschwind JF. Yttrium-90 microspheres: radiation therapy for unresectable liver cancer. J Vasc Interv Radiol. 2002;13(9 pt 2):S223–9.
Ariel IM, Padula G. Irradiation of the spleen by the intra-arterial administration of 90 yttrium microspheres in patients with malignant lymphoma: a preliminary report. Cancer. 1973;31:90–6.
Becker CD, Rosler H, Biasiutti FD, Baer HU. Congestive hypersplenism: treatment by means of radioembolization of the spleen with Y-90. Radiology. 1995;195:183–6.
Koda M, Ueki M, Maeda Y, et al. The influence on liver parenchymal function and complications of radiofrequency ablation or the combination with transcatheter arterial embolization for hepatocellular carcinoma. Hepatol Res. 2004;29:18–23.
Liu QD, Ma KS, He ZP, Ding J, Huang XQ, Dong JH. Experimental study on the feasibility and safety of radiofrequency ablation for secondary splenomagely and hypersplenism. World J Gastroenterol. 2003;9:813–7.
Varghese K, Viegas M, Adhyapak SM. A therapeutic dilemma – coronary artery stenting in the setting of thrombocytopaenia. Heart Lung Circ. 2015;24:e214–6.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Varghese, K., Adhyapak, S. (2017). Splenic Artery Embolization for Non-surgical Splenectomy. In: Therapeutic Embolization. Springer, Cham. https://doi.org/10.1007/978-3-319-42494-1_5
Download citation
DOI: https://doi.org/10.1007/978-3-319-42494-1_5
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-42492-7
Online ISBN: 978-3-319-42494-1
eBook Packages: MedicineMedicine (R0)