Abstract
A fundamental advance in evolution is the myelination of central and peripheral nerve fibers to enable vertebrates to think, react, and move far more quickly than what had been previously possible with unmyelinated nerve fibers within invertebrates. With the novel addition of myelin sheaths, nerve impulse propagation made a quantum leap forward in terms of the actual conduction velocity attainable by salutatory conduction of an action potential that becomes recharged at the regularly spaced gaps in the myelin insulation known as nodes of Ranvier.
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Meyer, M.A. (2016). Demyelinating Diseases of the Peripheral and Central Nervous System: Guillain–Barre and Multiple Sclerosis. In: Neurologic Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-39581-4_5
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DOI: https://doi.org/10.1007/978-3-319-39581-4_5
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