Skip to main content

Blood Transfusion Therapy for Patients with Sickle Cell Anemia

  • Chapter
  • First Online:
Medical and Surgical Complications of Sickle Cell Anemia
  • 1271 Accesses

Abstract

Sickle cell anemia is an inherited hemoglobinopathy that causes acute and chronic hemolytic anemia.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Further Reading

  • Alvarez O, Yovetich NA, Scott JP, et al. Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial. Am J Hematol. 2013;88:932.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Beverung LM, Strouse JJ, Hulbert ML, et al. Health-related quality of life in children with sickle cell anemia: impact of blood transfusion therapy. Am J Hematol. 2015;90:139.

    Article  PubMed  PubMed Central  Google Scholar 

  • Brittenham GM. Iron-chelating therapy for transfusional iron overload. N Engl J Med. 2011;364:146.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Davies SC, Roberts-Harewood M. Blood transfusion in sickle cell disease. Blood Rev. 1997;11:57.

    Article  CAS  PubMed  Google Scholar 

  • Goldstein AR, Anderson MJ, Serjeant GR. Parvovirus associated aplastic crisis in homozygous sickle cell disease. Arch Dis Child. 1987;62:585.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Howard J, Malfroy M, Llewelyn C, et al. The Transfusion Alternatives Preoperatively in Sickle Cell Disease (TAPS) study: a randomised, controlled, multicentre clinical trial. Lancet. 2013;381:930.

    Article  PubMed  Google Scholar 

  • Josephson CD, Su LL, Hillyer KL, Hillyer CD. Transfusion in the patient with sickle cell disease: a critical review of the literature and transfusion guidelines. Transfus Med Rev. 2007;21:118.

    Article  PubMed  Google Scholar 

  • Miller ST, Wright E, Abboud M, et al. Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle-cell anemia. J Pediatr. 2001;139:785.

    Article  CAS  PubMed  Google Scholar 

  • Quirolo K. How do I transfuse patients with sickle cell disease? Transfusion. 2010;50:1881.

    Article  PubMed  Google Scholar 

  • Vichinsky EP, Earles A, Johnson RA, et al. Alloimmunization in sickle cell anemia and transfusion of racially unmatched blood. N Engl J Med. 1990;322:1617.

    Article  CAS  PubMed  Google Scholar 

  • Vichinsky E, Bernaudin F, Forni GL, et al. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol. 2011;154:387.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wayne AS, Kevy SV, Nathan DG. Transfusion management of sickle cell disease. Blood. 1993;81:1109.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Al-Salem, A. (2016). Blood Transfusion Therapy for Patients with Sickle Cell Anemia. In: Medical and Surgical Complications of Sickle Cell Anemia. Springer, Cham. https://doi.org/10.1007/978-3-319-24762-5_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-24762-5_20

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-24760-1

  • Online ISBN: 978-3-319-24762-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics