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The Effect of Radiation on Acellular Dermal Matrix and Capsule Formation in Breast Reconstruction

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Breast Reconstruction

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Abstract

In the United States alone over 95,000 breast reconstructions were performed in 2013 (ASPS. Procedural Statistics, 2013). The two-stage tissue expander reconstruction accounts for over 75 % of these (J Am Coll Surg 217(4):656–664, 2013) and will likely continue to increase in prevalence as the healthcare industry evolves. Acellular dermal matrices (ADM) have become a key component in expander breast reconstruction due to a decrease in expansion time, lack of donor site morbidity, and improved definition of the inferior and lateral breast margins. At the same time, the indications for post-mastectomy radiation are expanding as new data supports an improved safety and efficacy profile (J Clin Oncol 28(14):2396–2403, 2010; Strahlenther Onkol 185(10):656–662, 2009). Therefore, surgeons must understand the effects of radiation on dermal matrices and counsel patients on the safety and complication rates of expander/ADM reconstruction subjected to post-mastectomy radiation.

Disclosure

Dr. Moyer is a consultant for Mentor Corporation and founder of AcCellerate Skin Rejuvenation system. He has nothing to disclose in regards to this manuscript.

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Authors and Affiliations

  1. Division of Plastic and Reconstructive Surgery, Emory University, 975 Johnson Ferry Road NE, Suite 100, Atlanta, GA, 30342, USA

    Hunter R. Moyer M.D.

  2. Atlanta Plastic Surgery, 975 Johnson Ferry Road NE, Suite 100, Atlanta, GA, 30342, USA

    Hunter R. Moyer M.D. & Mandi Charles RNFA

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  1. Hunter R. Moyer M.D.
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  2. Mandi Charles RNFA
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Correspondence to Hunter R. Moyer M.D. .

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  1. Tustin, California, USA

    Melvin A. Shiffman

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Moyer, H.R., Charles, M. (2016). The Effect of Radiation on Acellular Dermal Matrix and Capsule Formation in Breast Reconstruction. In: Shiffman, M. (eds) Breast Reconstruction. Springer, Cham. https://doi.org/10.1007/978-3-319-18726-6_113

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  • DOI: https://doi.org/10.1007/978-3-319-18726-6_113

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18725-9

  • Online ISBN: 978-3-319-18726-6

  • eBook Packages: MedicineMedicine (R0)

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