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The Endometrium in Adenomyosis

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Uterine Adenomyosis

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Abstract

The observation has long been reported of direct continuity between the eutopic and the ectopic endometrial glands in adenomyosis. Recent evidence point to the existence of differences between the endometrium in adenomyosis compared to control endometrium including increased ‘invasiveness’ in adenomyosis. Differences were also reported between the eutopic endometrium in adenomyosis and endometriosis. However, almost all published literature suffers from methodological weaknesses including inadequate control for cycle phase and symptoms. This calls for caution when interpreting the findings or drawing conclusions relevant to the pathophysiology of adenomyosis.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, University Hospitals of Leicester, Leicester, UK

    Marwan Habiba PhD, PhD, FRCOG

  2. Department of Health Sciences, University of Leicester, Leicester, UK

    Marwan Habiba PhD, PhD, FRCOG

  3. Department of Gynaecology, Obstetrics and Urology, Sapienza University, Rome, 00161, Italy

    Giuseppe Benagiano MD, PhD, FRCOG

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  1. Marwan Habiba PhD, PhD, FRCOG
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  2. Giuseppe Benagiano MD, PhD, FRCOG
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Correspondence to Marwan Habiba PhD, PhD, FRCOG .

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Editors and Affiliations

  1. Obstetrics and Gynaecology, University Hospitals of Leicester, Leicester, United Kingdom

    Marwan Habiba

  2. Gynaecology, Obstetrics and Urology, Sapienza University, Rome, Italy

    Giuseppe Benagiano

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Habiba, M., Benagiano, G. (2016). The Endometrium in Adenomyosis. In: Habiba, M., Benagiano, G. (eds) Uterine Adenomyosis. Springer, Cham. https://doi.org/10.1007/978-3-319-13012-5_6

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  • DOI: https://doi.org/10.1007/978-3-319-13012-5_6

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