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Neurosurgical Aspects of Hypothalamic Disease

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The Human Hypothalamus

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Lesions within the hypothalamus pose many difficulties for a neurosurgeon – the intricate anatomy and numerous critical structures surrounding it make the hypothalamus a difficult region of the brain to access. When considering neurosurgical management of hypothalamic lesions, there are a number of possible approaches dependent on the type of lesion and the location within the thalamus. Numerous lesions and diseases can involve the hypothalamus, resulting in compromised function of numerous endocrine systems, sleep-wake cycle, vision, memory, and emotional regulation. When these lesions arise and surgical management is indicated, there are five well-reported approaches to these lesions – each with their benefits and associated risks/considerations for surgical approach. A solid foundational knowledge of the anatomy of the region surrounding the hypothalamus, characteristics of the lesion itself, and the specific location of the lesion in question guide the choice of surgical approach when assessing hypothalamic disease.

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Author information

Authors and Affiliations

  1. Department of Surgery, Division of Neurosurgery, University of Connecticut Health Center, UConn Health, Farmington, CT, USA

    Ketan R. Bulsara

  2. School of Medicine, UConn Health, Farmington, CT, USA

    Joshua Knopf

  3. School of Medicine, University of Connecticut Health Center, Farmington, CT, USA

    Rebecca Calafiore

  4. University of Connecticut School of Medicine, Farmington, CT, USA

    Anzhela D. Moskalik

Authors
  1. Ketan R. Bulsara
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  2. Joshua Knopf
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  3. Rebecca Calafiore
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  4. Anzhela D. Moskalik
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Corresponding author

Correspondence to Ketan R. Bulsara .

Editor information

Editors and Affiliations

  1. Department of Endocrinology, Diabetes, Metabolism and Weight Management, Ochsner Medical Center, New Orleans, LA, USA

    Gabriel I. Uwaifo

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Bulsara, K.R., Knopf, J., Calafiore, R., Moskalik, A.D. (2021). Neurosurgical Aspects of Hypothalamic Disease. In: Uwaifo, G.I. (eds) The Human Hypothalamus. Contemporary Endocrinology. Humana, Cham. https://doi.org/10.1007/978-3-030-62187-2_9

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  • DOI: https://doi.org/10.1007/978-3-030-62187-2_9

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-62186-5

  • Online ISBN: 978-3-030-62187-2

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