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Kidney Failure Associated with Polycompartment Syndrome

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Compartment Syndrome

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

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Abstract

The detrimental effects of elevated intra-abdominal pressure (IAP) on kidney function have been known for centuries. However, only recently there has been an increasing focus on the potential role of venous congestion in the development of renal failure, through coexisting repercussions on the heart and abdominal compartment. In contrast with the traditional perception of worsening renal function due to hypoperfusion, this chapter discusses the pathophysiological insights on kidney injury induced by intra-abdominal hypertension (IAH) and the role of IAP in worsening renal function in the setting of decompensated heart failure, introducing the new concept of “cardio-abdominal-renal syndrome” (CARS).

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Abbreviations

ACS:

Abdominal compartment syndrome

ADHF:

Acute decompensated heart failure

APP:

Abdominal perfusion pressure

ARF:

Advanced renal failure

BP:

Blood pressure

CABG:

Coronary artery bypass surgery

CARS:

Cardio-abdominal-renal syndrome

CCU:

Cardiac/coronary care unit

CrCl:

Creatinine clearance

CVP:

Central venous pressure

EVLWI:

Extravascular lung water index

FG:

Filtration gradient

GEDVI:

Global end-diastolic volume index

GFP:

Glomerular filtration pressure

GFR:

Glomerular filtration rate

HF:

Heart failure

HJR:

Hepatojugular reflux

IAH:

Intra-abdominal hypertension

IAP:

Intra-abdominal pressure

ICU:

Intensive care unit

ITP:

Intrathoracic pressure

IVCCI:

Inferior vena cava collapsibility index

JVP:

Jugular venous pressure

MAP:

Mean arterial pressure

MV:

Mechanical ventilation

PAOP:

Pulmonary artery occlusion pressure

PAP:

Pulmonary artery pressure

PTP:

Proximal tubular pressure

RVP:

Renal venous pressure

STEMI:

ST-elevation myocardial infarction

WRF:

Worsening renal function

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Author information

Authors and Affiliations

  1. Department of Intensive Care Medicine, University Hospital Brussels (UZB), Jette, Belgium

    Andrea Minini & Manu L. N. G. Malbrain

  2. Department of Intensive Care Medicine and Anaesthesia, University of Insubria, Varese, Italy

    Andrea Minini

  3. Division of Intensive Care, Santa Cabrini Hospital, Montreal, QC, Canada

    Philippe Rola

  4. Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), Jette, Belgium

    Manu L. N. G. Malbrain

  5. International Fluid Academy, Jette, Belgium

    Manu L. N. G. Malbrain

Authors
  1. Andrea Minini
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Corresponding author

Correspondence to Manu L. N. G. Malbrain .

Editor information

Editors and Affiliations

  1. General, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy

    Federico Coccolini

  2. Intensive Care Unit, Ziekenhuisnetwerk Antwerpen Stuivenberg, Antwerpen, Belgium

    Manu L.N.G. Malbrain

  3. Regional Trauma Services, Foothills Medical Centre, Calgary, AB, Canada

    Andrew W Kirkpatrick

  4. Chief Physician in Intensive Care Unit and Trauma Management in Level-1 Trauma Center, “M. Bufalini” Hospital, CESENA, Forli/Cesana, Italy

    Emiliano Gamberini

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Minini, A., Rola, P., Malbrain, M.L.N.G. (2021). Kidney Failure Associated with Polycompartment Syndrome. In: Coccolini, F., Malbrain, M.L., Kirkpatrick, A.W., Gamberini, E. (eds) Compartment Syndrome. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-55378-4_14

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  • DOI: https://doi.org/10.1007/978-3-030-55378-4_14

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