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Pulmonary Infections in the Immunocompromised Host

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Diagnostic and Interventional Bronchoscopy in Children

Part of the book series: Respiratory Medicine ((RM))

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Abstract

Pulmonary infections are common complications in immunocompromised children, particularly hematopoietic stem cell transplantation, solid organ transplantation, and primary immunodeficiency patients. These infections may be due to common pathogens seen in all children or pathogens specific to immunocompetent hosts. In the setting of immune compromise, patients have a higher risk of morbidity and mortality secondary to pulmonary disease. Clinical symptoms and imaging findings are less predictable in immunocompromised patients. Therefore, diagnosis often requires consideration of their current immune status, an extensive exposure history, and invasive studies such as bronchoalveolar lavage or biopsy. With multiple pathogens often contributing to disease in immunocompromised hosts, identification of all pathogens is important.

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Authors and Affiliations

  1. Department of Pediatrics, Yale University, New Haven, CT, USA

    Inci Yildirim

  2. Department of Pediatrics, Children’s Hospital Los Angeles, Los Angeles, CA, USA

    Joy Gibson

  3. Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USA

    Lara Danziger-Isakov

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  2. Joy Gibson
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  3. Lara Danziger-Isakov
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Correspondence to Lara Danziger-Isakov .

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  1. Division of Pulmonary Medicine, Children’s Hospital of Philadelphia Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, USA

    Samuel Goldfarb

  2. Division of Pulmonary Medicine & Center for Pediatric Airway Disorders, Children’s Hospital of Philadelphia University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Joseph Piccione

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Yildirim, I., Gibson, J., Danziger-Isakov, L. (2021). Pulmonary Infections in the Immunocompromised Host. In: Goldfarb, S., Piccione, J. (eds) Diagnostic and Interventional Bronchoscopy in Children. Respiratory Medicine. Humana, Cham. https://doi.org/10.1007/978-3-030-54924-4_20

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  • DOI: https://doi.org/10.1007/978-3-030-54924-4_20

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  • Publisher Name: Humana, Cham

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  • Online ISBN: 978-3-030-54924-4

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