Skip to main content
SpringerLink
Log in

Basic Cardiovascular Pharmacology

  • Chapter
  • First Online:
Cardiac Anesthesia

  • 1612 Accesses

Abstract

In addition to having a thorough understanding of cardiovascular anatomy and pathophysiology and sophisticated monitoring facilities, the anesthesia provider engaged with caring for cardiac surgery patients must have a strong command of the pharmacology of the agents used in this setting. This chapter describes briefly the pharmacology of the most commonly used medications in the perioperative management of cardiac surgery patients.

Medicine heals doubts as well as diseases.

—Karl Marx

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

BP:

Blood pressure

cAMP:

Cyclic adenosine monophosphate

CPB:

Cardiopulmonary bypass

cGMP:

Cyclic guanosine monophosphate

HIT:

Heparin-induced thrombocytopenia

LV:

Left ventricle or left ventricular

MAO:

Monoamine oxidase

MAP:

Mean arterial pressure

PCC:

Prothromobin complex concentrate

PDA:

Phosphodiesterase

SVR:

Systemic vascular resistance

Further Reading

  1. Abbott TR. The use of glucagon following open heart surgery in children. Br J Anesth. 1972;44(8):854–8.

    Article  CAS  Google Scholar 

  2. Bojar RM. Manual of perioperative care in adult cardiac surgery. Chichester: Wiley-Blackwell; 2011.

    Google Scholar 

  3. Cheng DCH, David TE, Cheng DC. Perioperative care in cardiac anesthesia and surgery. Philadelphia: Wolters Kluwer Health; 2015.

    Google Scholar 

  4. Goodman LS, Brunton LL, Chabner B, Knollmann BC. Goodman & Gilman’s pharmacological basis of therapeutics. 12th ed. New York: McGraw-Hill; 2011. Print

    Google Scholar 

  5. Hemmings HC, Talmage E. Pharmacology and physiology for anesthesia. 2nd ed. Philadelphia: Elsevier; 2019. Print

    Google Scholar 

  6. Kazama T, Ikeda K, Morita K. Reduction by fentanyl of the Cp50 values of propofol and hemodynamic responses to various noxious stimuli. Anesthesiology. 1997;87:213.

    Article  CAS  Google Scholar 

  7. MacKenzie M, Zed PJ, Ensom MH. Opioid pharmacokinetics-pharmacodynamics: clinical implications in acute pain management in trauma. Ann Pharmacother. 2016;50:209.

    Article  CAS  Google Scholar 

  8. Shore-Lesserson L. The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: clinical practice guidelines – anticoagulation during cardiopulmonary bypass. Ann Thorac Surg. 2018;105:650–62.

    Article  Google Scholar 

  9. Short TG, Plummer JL, Chui PT. Hypnotic and anaesthetic interactions between midazolam, propofol, and alfentanil. Br J Anaesth. 1992;69:162.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anesthesiology and Perioperative Medicine, Cooper University Hospital, Camden, NJ, USA

    Ahmed S. Awad & Megan Linehan

  2. Department of Pharmacy, Cooper University Hospital, Camden, NJ, USA

    Danielle Evans & Lauren A. Igneri

  3. Department of Anesthesiology and Perioperative Medicine, Cooper University Hospital, Camde, Browns Mills, NJ, USA

    Muhammed Muntazar

Authors
  1. Ahmed S. Awad
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Megan Linehan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Danielle Evans
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Lauren A. Igneri
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Muhammed Muntazar
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ahmed S. Awad .

Editor information

Editors and Affiliations

  1. Department of Anesthesiology, Cooper Medical School of Rowan University/Cooper University Health Care, Camden, NJ, USA

    Ahmed S. Awad, MD, MBA

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Awad, A.S., Linehan, M., Evans, D., Igneri, L.A., Muntazar, M. (2021). Basic Cardiovascular Pharmacology. In: Awad, MD, MBA, A.S. (eds) Cardiac Anesthesia. Springer, Cham. https://doi.org/10.1007/978-3-030-51755-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-51755-7_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-51754-0

  • Online ISBN: 978-3-030-51755-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation