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Phyllodes Tumor of the Breast in Pregnancy and Lactation

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Diseases of the Breast during Pregnancy and Lactation

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1252))

Abstract

Phyllodes tumor constitutes around 1% of all and 2.5% of fibroepithelial breast lumps. Three types including benign, borderline, and malignant tumors have been described. The benign variant is the most common, is close to fibroadenoma, but is usually larger and recurs more frequently. The rare malignant type is aggressive. Standard treatment consists of lumpectomy with appropriate margins for benign phyllodes tumor, while the borderline and malignant variants must be treated by wide resection or mastectomy. Phyllodes tumor is a rare tumor in pregnancy and lactation, and the effect of gestational alterations in hormone levels on this tumor have not been discussed in the literature, except for several case reports. In summary and alluding to our recent literature review, large size, fast growth, bilaterality, and probably malignancy are more commonly expected in gestational phyllodes tumors.

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Authors and Affiliations

  1. Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran

    Sadaf Alipour

  2. Department of Surgery, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Sadaf Alipour

  3. Deputy of Education, Ministry of Health, Tehran, Iran

    Amirhossein Eskandari

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  1. Sadaf Alipour
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  2. Amirhossein Eskandari
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Correspondence to Sadaf Alipour .

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Editors and Affiliations

  1. Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran

    Sadaf Alipour

  2. Breast Disease Research Center (BDRC), Tehran University of Medical Sciences, Tehran, Iran

    Ramesh Omranipour

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Alipour, S., Eskandari, A. (2020). Phyllodes Tumor of the Breast in Pregnancy and Lactation. In: Alipour, S., Omranipour, R. (eds) Diseases of the Breast during Pregnancy and Lactation. Advances in Experimental Medicine and Biology, vol 1252. Springer, Cham. https://doi.org/10.1007/978-3-030-41596-9_19

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