Abstract
Glomus tumor is a rare benign neoplasm composed of cells with a phenotype akin to the modified perivascular muscle cells of the cutaneous glomus body. Primary intraosseous glomus tumor is extremely rare. Most tumors are diagnosed in patients 20–40 years old. Excruciating pain is the hallmark of this tumor. In contrast to osteoid osteoma, it has a paroxysmal pattern and does not respond to salicylates. Most cases occur in the fingers, usually in a subungueal location. Feet are also a frequent site. Radiographs show a lucent, well-defined nodular depression in the cortex of the distal phalanx. Tumor cells are round in glomus tumor, but may be elongated in glomangiomyoma. Immunohistochemically, the tumors are positive for smooth muscle markers. Marginal resection or curettage is curative for benign tumors.
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Zhang, Y., Rosenberg, A.E. (2020). Glomus Tumor. In: Santini-Araujo, E., Kalil, R.K., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, Cham. https://doi.org/10.1007/978-3-030-28315-5_37
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DOI: https://doi.org/10.1007/978-3-030-28315-5_37
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