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Management of Fertility in Male Cancer Patients

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Male Infertility

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Abstract

Cancer survival rates have improved dramatically over the last couple of decades due to advances in diagnostic techniques and therapies. Roughly 15% of cases of newly diagnosed cancer in men are in those younger than 55 years of age, and about one quarter of them are younger than age 20. Consequently, the population of young cancer survivors has grown, and the focus of cancer treatments has shifted from one of survival alone to that of survival and quality of life after treatment. For many men and their families, the maintenance and preservation of fertility during and after treatment is important. However, antineoplastic agents, radiation, and surgical therapies can all pose significant threats to a man’s fertility potential, as can the presence of cancer itself. Male infertility due to cancer treatments may be temporary or permanent and can range from mild to severe. Because it is difficult—if not impossible—to predict the exact impact of cancer therapy on an individual man’s ability to father a biological child, sperm cryopreservation prior to therapy remains the cornerstone of fertility preservation in this patient population. Unfortunately, in many cases, sperm cryopreservation remains underutilized. When sperm has not been banked prior to treatment and when men are azoospermic by their cancer treatment, surgical sperm retrieval in conjunction with advanced reproductive technologies (ART) is offered.

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  1. Department of Urology, University of Wisconsin Hospital and Clinics, 1685 Highland Avenue, Madison, WI, 53719, USA

    Daniel H. Williams IV MD

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  1. Daniel H. Williams IV MD
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Correspondence to Daniel H. Williams IV MD .

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  1. University of Florida, Director, Robotic Surgery, Winter Haven Hospital &, 200 Avenue F. N.E., Winter Haven, 33881, Florida, USA

    Sijo J. Parekattil

  2. Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Euclid Avenue 9500, Cleveland, 44195, Ohio, USA

    Ashok Agarwal

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Williams, D.H. (2012). Management of Fertility in Male Cancer Patients. In: Parekattil, S., Agarwal, A. (eds) Male Infertility. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3335-4_17

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