Abstract
This chapter gives an overview of the management of incidental findings on neuroimaging in the population-based Rotterdam Study, in which brain MRI was introduced as part of the core study protocol in 2005 (1.5 T). To this purpose, a protocol for the management of incidental findings was defined by a group of experts from different fields. During the study, all brain scans are reviewed for incidental findings by group of trained researchers, under the supervision of a neuroradiologist. Only findings deemed of potential clinical relevance (according to the study protocol) are reported to the participants. Overall, incidental findings that require additional clinical review by a medical specialist, of which meningiomas and aneurysms are most common, occur in just over 3%. The vast majority of these undergo a watch and wait policy, indicating that clinical consequences are in most cases limited.
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References
Bos D, Poels MMF, Adams HHH, Akoudad S, et al (2016) Prevalence, clinical management and natural course of incidental findings on brain MRI: A population-based imaging study. Radiol. In press
Hofman A, Brusselle GG, Darwish Murad S et al (2015) The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol 30:661–708
Ikram MA, van der Lugt A, Niessen WJ et al (2015) The Rotterdam Scan Study: design update 2016 and main findings. Eur J Epidemiol 30:1299–1315
ISUIA (1998) Unruptured intracranial aneurysms – risk of rupture and risks of surgical intervention. International Study of Unruptured Intracranial Aneurysms Investigators. N Engl J Med 339:1725–1733
Morris Z, Whiteley WN, Longstreth WT Jr et al (2009) Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 339:b3016
Mozaffarian D, Benjamin EJ, Go AS et al (2016) Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation 133:e38–e360
Prince M, Bryce R, Albanese E et al (2013) The global prevalence of dementia: a systematic review and metaanalysis. Alzheimers Dement 9(63–75):e62
van der Lugt A (2009) Incidental findings on brain magnetic resonance imaging. BMJ 339:b3107
Vernooij MW, Ikram MA, Tanghe HL et al (2007) Incidental findings on brain MRI in the general population. N Engl J Med 357:1821–1828
Wiebers DO, Whisnant JP, Huston J 3rd et al (2003) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet 362:103–110
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© 2016 Springer International Publishing Switzerland
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Bos, D., Vernooij, M.W. (2016). Management of Incidental Findings on Neuroimaging in the Rotterdam Study. In: Weckbach, S. (eds) Incidental Radiological Findings. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2016_53
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DOI: https://doi.org/10.1007/174_2016_53
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Publisher Name: Springer, Cham
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