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Cell Cycle Activation and Cell Death in the Nervous System

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Cell-Cycle Mechanisms and Neuronal Cell Death

Part of the book series: Neuroscience Intelligence Unit ((NIU.LANDES))

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Abstract

The discovery of the cell division cycle opened new avenues for the understanding of cancer as well as in the search for therapy. However, the implications of the discovery had a more profound effect on biological research than anticipated at the time. We can now clearly distinguish between the activation of the cell division cycle and cell division itself. We also have closer understanding of the differences between senescence, quiescence and terminal differentiation. Furthermore the elucidation of the mechanisms that regulate the cell cycle also means that we have now begun to understand the mechanisms that link cell division and cell death.

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Authors and Affiliations

  1. Neuroscience Division Medical School, University of Birmingham, Birmingham, UK

    Zsuzsanna Nagy

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  1. Zsuzsanna Nagy
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Editors and Affiliations

  1. Department of Pharmaceutical Sciences, University of Catania, Catania, Italy

    Agata Copani M.D., Ph.D.

  2. Department of Human Physiology and Pharmacology, University of Rome “La Sapienza”, Rome, Italy

    Ferdinando Nicoletti M.D.

  3. I.N.M. Neuromed, Pozzilli, Italy

    Ferdinando Nicoletti M.D.

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Nagy, Z. (2005). Cell Cycle Activation and Cell Death in the Nervous System. In: Copani, A., Nicoletti, F. (eds) Cell-Cycle Mechanisms and Neuronal Cell Death. Neuroscience Intelligence Unit. Springer, Boston, MA. https://doi.org/10.1007/0-387-29390-6_4

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