Abstract
Toxoplasma gondii is one of the most common causes of latent infections in humans and animals. Although T. gondii infection is widely prevalent in the world, most acquired cases of the disease are asymptomatic. The important aspect of this parasitic infection is the probable danger of congenital transmission and its severe effects on the fetus. There have been many reports about the prevalence of anti-T. gondii antibody among different groups of people in Iran; however the epidemiological data in mentally retarded patients are rare. The present study was conducted on 158 mentally retarded persons (94 males, 64 females) in the rehabilitation centers of Khoramabad from autumn 2012 to winter 2013. The overall prevalence of anti-T. gondii antibody was 30.4 % (48 cases). There were no significant difference between sex and toxoplasmosis (p > 0.05). However, there were no statistically significant difference between age and toxoplasmosis, nevertheless the prevalence of toxoplasmosis in the patients less than 10-years-old had significantly the lowest rate. The highest infection rates were found in the two age groups of 10–19 and ≥30 years old. Our results showed that the prevalence of toxoplasmosis in the mentally retarded persons in the rehabilitation centers of Khorramabad was similar to the prevalence in pregnant women in this city. Therefore, the disease does not cause additional danger to this group of women.
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References
Ajami A, Sharif M, Ziaee H (2005) Serological study of toxoplasmosis in Mazandaran rehabilitation centers. J Mazandaran University Med Sci 15(46):64–69
Allain JP, Palmer CR, Pearson G (1998) Epidemiological study of latent and recent infection by Toxoplasma gondii in pregnant women from a regional population in the UK. J Infect 36(2):189–196
Amrei M, Al-Hamshary A, Fotoh O, Abdel-Rahman S (1999) Studies on prenatal infections in children with unknown cause of mental retardation and examination of their mothers. J Egypt Soc Parasitol 29(1):59–67
Asmar M, Habibpour R, Amirkhani A (1999) Seroepidemiology of toxoplasmosis in rehabilitation centers of Gilan province. The eighth national congress of infectious diseases in Iran, p 28
Black MW, Boothroyd JC (2000) Lytic cycle of Toxoplasma gondii. Microbiol Mol Biol Rev 64(3):607–623
Caiaffa WT, Chiari CA, Figueiredo AR, Orefice F, Antunes CM (1993) Toxoplasmosis and mental retardation: report of a case–control study. Memórias do Instituto Oswaldo Cruz 88(2):253–261
Cheraghipour K, Taherkhani H, Falah Mohammad SA, Sardarian K, Rostamnezhad M, Maghsoudi A (2010) Seroprevalence of toxoplasmosis in pregnant women admitted to the health centers of Khorram-Abad City, Iran. Sci J Hamadan University Med Sci Health Serv 17(3):46–51
Daryani A, Sharif M, Meigouni M (2011) Seroprevalence of IgG and IgM anti Toxoplasma antibodies in HIV/AIDS patients, northern Iran. Asian Pac J Trop Med 4(4):271–274
Dubey JP (2009) Toxoplasmosis of animals and humans. CRC Press, Boca Raton
Elbez-Rubinstein A, Ajzenberg D, Dardé M-L, Cohen R, Dumètre A, Yera H, Gondon E, Janaud J-C, Thulliez P (2009) Congenital toxoplasmosis and reinfection during pregnancy: case report, strain characterization, experimental model of reinfection, and review. J Infect Dis 199(2):280–285
Ertug S, Okyay P, Turkmen M, Yuksel H (2005) Seroprevalence and risk factors for toxoplasma infection among pregnant women in Aydin province, Turkey. BMC Public Health 5(1):66
Fallahi S, Badparva E, Mohammadi M, Ebrahimzadeh F, Pournia Y (2009) Seroepidemiological study of Toxoplasma gondii in women referred to Khorramabad laboratory of health center for medical examination before marriage, Lorestan Province, Iran, 2008. Asian J Biol Sci 2(3):88–94
Farid H, Sharif M (1990) Serological prevalence of toxoplasmosis in rehabilitation centers of Esfahan province. The first national congress of parasitology in Iran, p 45
Gharavi M, Rahnama N, Jahani M (2005) Seroepidemiological survey of toxoplasma infections of mentally retarded children. Iran J Public Health 34(1):19–22
Griffin L, Williams KA (1983) Serological and parasitological survey of blood donors in Kenya for toxoplasmosis. Trans R Soc Trop Med Hyg 77(6):763–766
Jones J, Lopez A, Wilson M (2003) Congenital toxoplasmosis. Am Fam Physician 67(10):2131–2146
Lee Y-H, Noh H-J, Hwang O-S, Lee S-K, Shin D-W (2000) Seroepidemiological study of Toxoplasma gondii infection in the rural area Okcheon-gun, Korea. Korean J Parasitol 38(4):251–256
Linguissi LSG, Nagalo BM, Bisseye C, Kagoné TS, Sanou M, Tao I, Benao V, Simporé J, Koné B (2012) Seroprevalence of toxoplasmosis and rubella in pregnant women attending antenatal private clinic at Ouagadougou, Burkina Faso. Asian Pac J Trop Med 5(10):810–813
Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado Y (2011) Infectious diseases of the fetus and newborn: expert consult. Elsevier, Philadelphia
Rostami MN, Eskandari E, Garoosi Z, Mohajeri N, Rezaian M, Keshavarz H (2006) Serological Study of Toxoplasma gondii infection using IFA method in renal transplant recipients. Iran J Parasitol 1(1):31–38
Saleh MMS, AL-Shamiri AH, Qaed AA (2010) Seroprevalence and Incidence of Toxoplasma gondii among apparently healthy and visually or hearing disabled children in Taiz City, Yemen. Korean J Parasitol 48(1):71–73
Sharif M, Ajami A, Daryani A, Ziaei H, Khalilian A (2006) Serological survey of toxoplasmosis in women referred to medical health laboratory before marriage northern Iran 2003–2004. Int J Mol Med Adv Sci 2(2):134–137
Sharif M, Ziaei H, Daryani A, Ajami A (2007) Seroepidemiological study of toxoplasmosis in intellectual disability children in rehabilitation centers of northern Iran. Res Dev Disabil 28(3):219–224
Shimelis T, Tebeje M, Tadesse E, Tegbaru B, Terefe A (2009) Sero-prevalence of latent Toxoplasma gondii infection among HIV-infected and HIV-uninfected people in Addis Ababa, Ethiopia: a comparative cross-sectional study. BMC Res Notes 2(1):213
Shin D-W, Cha D-Y, Hua QJ, Cha G-H, Lee Y-H (2009) Seroprevalence of Toxoplasma gondii infection and characteristics of seropositive patients in general hospitals in Daejeon, Korea. Korean J Parasitol 47(2):125–130
Shirbazou SS, Abasian L, Talebi Meymand F (2011) Effects of Toxoplasma gondii infection on plasma testosterone and cortisol level and stress index on patients referred to Sina hospital, Tehran. Jundishapur J Microbiol 4(3):167–173
Terazawa A, Muljono R, Susanto L, Margono S, Konishi E (2003) High Toxoplasma antibody prevalence among inhabitants in Jakarta, Indonesia. Jpn J Infect Dis 56(3):107–109
Walle F, Kebede N, Tsegaye A, Kassa T (2013) Seroprevalence and risk factors for Toxoplasmosis in HIV infected and non-infected individuals in Bahir Dar, Northwest Ethiopia. Parasites Vectors 6(1):1–8
Weiss LM, Dubey JP (2009) Toxoplasmosis: a history of clinical observations. Int J Parasitol 39(8):895–901
Wen L, Liu L, Ao L, Chen S, Zeng W, Ling X (2003) Effect of toxoplasma infection during pregnancy to the development of fetus and infant. Zhonghua fu chan ke za zhi 38(6):331–333
Wong S-Y, Remington JS (1994) Toxoplasmosis in pregnancy. Clin Infect Dis 18:853–861
Acknowledgments
This study was financially supported by Deputy for research and technology affairs of Lorestan University of Medical Sciences (Grant number: TARH 89/25). The authors appreciate of vice-chancellor for research and health and Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, for their sincere cooperation. Also we thank all of those people who helped us in this research.
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Ezatpour, B., Zibaie, M., Rahmati, H. et al. Seroprevalence of toxoplasmosis in mentally retarded patients in Iranian rehabilitation centers. J Parasit Dis 39, 13–17 (2015). https://doi.org/10.1007/s12639-013-0358-6
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DOI: https://doi.org/10.1007/s12639-013-0358-6