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Pseudomyxoma peritonei arising from intraductal papillary neoplasm after surgical pancreatectomy: report of 2 cases and review of the literature

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Abstract

We report 2 cases of pseudomyxoma peritonei (PMP) combined with an intraductal papillary mucinous neoplasm (IPMN) and a review of the literature. In both cases, PMP emerged after surgical resection of the IPMN. In one case, neoplastic foci were present in the surgical margin and PMP was found 1 year after the initial resection, while PMP emerged 5 years after surgical resection in the other case. Including these 2 cases, 8 cases of PMP arising from IPMN have been reported. This condition occurs more frequently in males (7 males, 1 female), while the age at diagnosis ranges from 49 to 82 years, with a mean of 63.3 years. IPMNs occur more commonly in the tail of the pancreas (62.5%). Two different patterns regarding the mechanism of PMP arising from IPMN have been indicated; a rupture of the pancreatic duct, after which the neoplasm spreads through the fistula into the peritoneal cavity, and post-surgical development of PMP after insufficient surgical treatment for an IPMN. Our findings indicate that attention must be given to avoid mucous leakage and obtain a negative surgical margin during surgical treatment of an IPMN.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Gastroenterology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan

    Hiroshi Imaoka, Kenji Yamao, Susumu Hijioka, Kazuo Hara, Nobumasa Mizuno, Tsutomu Tanaka, Shinya Kondo, Masahiro Tajika & Yasumasa Niwa

  2. Department of Gastrointestinal Surgery, Aichi Cancer Center Hospital, Nagoya, 464-8681, Japan

    Yasuhiro Shimizu

Authors
  1. Hiroshi Imaoka
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  2. Kenji Yamao
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  3. Susumu Hijioka
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  4. Kazuo Hara
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  5. Nobumasa Mizuno
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  6. Tsutomu Tanaka
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  7. Shinya Kondo
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  8. Masahiro Tajika
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  9. Yasuhiro Shimizu
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  10. Yasumasa Niwa
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Correspondence to Kenji Yamao.

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Imaoka, H., Yamao, K., Hijioka, S. et al. Pseudomyxoma peritonei arising from intraductal papillary neoplasm after surgical pancreatectomy: report of 2 cases and review of the literature. Clin J Gastroenterol 5, 15–19 (2012). https://doi.org/10.1007/s12328-011-0279-9

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  • DOI: https://doi.org/10.1007/s12328-011-0279-9

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