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Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in A Child: A Case Report

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Abstract

Philadelphia chromosome (Ph1)-positive Chronic Myelogenous Leukemia (CML) in a child below the age of 3 years is extremely rare. We have reported such a case in a 3 year old male child. Peripheral blood smear revealed features of CML and karyotypic study showed (Ph1) positivity. Biologic behaviour and prognosis are similar to that of adult-type of CML.

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References

  1. Lichtman MA, Liesveld JL (2006) Chronic myelogenous leukemia and related disorders. In: Lichtman MA, Beutler E, Kipps TJ, Seligsohn U, Kaushansky K, Prchal JT (eds) Williams hematology, 7th edn. McGraw-Hill Companies Inc, USA, pp 1237–1294

    Google Scholar 

  2. Castro-malaspina H, Schaison G, Breire J, Passe S, Briere J, Pasquer A, Tanzer J, Jacquillat C, Bernard J (1983) Philadelphia chromosome-positive chronic myelocytic leukemia in children—survival and prognostic factors. Cancer 52:721–727

    Article  CAS  PubMed  Google Scholar 

  3. Rowe JM, Lichtman MP (1984) Hyperleukocytosis and leukostasis: common features of childhood chronic myeloid leukemia. Blood 63:1230

    CAS  PubMed  Google Scholar 

  4. Roberts IAG, Dokal IS (2001) Adult-type chronic myeloid leukemia. In: Lilleyman J, Hann I, Blanchette V (eds) Pediatric hematology, 2nd edn. Churchill Livingstone, London, pp 419–436

    Google Scholar 

  5. Reichard KK, Larson RS, Rabinowitz I (2009) Chronic myelogenous leukemia. In: Green JP, Foerster J, Rodgers GM, Paraskevas F, Glader B, Arber DA, Means RT Jr (eds) Wintrobe’s clinical hematology, vol 2, 12th edn. Lippincott Williams and Wilkins, USA, pp 2006–2030

    Google Scholar 

  6. Goldmann JM, Mughal TI (2005) Chronic myeloid leukemia. In: Hoffbrand AV, Catovsky D, Tuddenham EGD (eds) Postgraduate hematology, 5th edn. Blackwell Publishing, Wiley India Pvt Ltd, New Delhi, pp 603–618

    Chapter  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, S.C.B. Medical College, Cuttack, 753007, Orissa, India

    Aparajita Mishra, Kalpalata Tripathi, Lity Mohanty & Sujata Pujari

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  1. Aparajita Mishra
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  2. Kalpalata Tripathi
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  3. Lity Mohanty
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  4. Sujata Pujari
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Correspondence to Aparajita Mishra.

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Mishra, A., Tripathi, K., Mohanty, L. et al. Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in A Child: A Case Report. Indian J Hematol Blood Transfus 26, 109–110 (2010). https://doi.org/10.1007/s12288-010-0042-2

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  • DOI: https://doi.org/10.1007/s12288-010-0042-2

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