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Radial Scar-Significant Diagnostic Challenge

  • Original Paper
  • Published:
Pathology & Oncology Research

Abstract

The prevalence of radial scar (RS) is 0.04% in asymptomatic women participating in population screening for breast cancer. It is important to differentiate RS from concomitant malignancies, which occur in 20–30% of patients, or from small stellate carcinomas which give similar radiomorphology. The aim of our study was to evaluate the effectivity of current breast diagnostic methods in distinguishing between real RS, concomitant malignancy and carcinomas imitating RS. Diagnosis of RS was set up in 61 cases by mammography. Forty-four patients underwent surgical excision: histology showed benign or malignant lesions in 28 and 16 cases, respectively. A series of negative results at follow-up proved the benign nature of the lesion in further 11 cases. Six patients were not available for follow-up. Results of mammography, physical examination, ultrasonography and cytology were evaluated and were compared in 39 benign and 16 malignant cases. Results of examinations were reported on the BI-RADS scale ranging from 1 to 5. The mean categorical scores of all diagnostic processes were around the level of borderline lesions: mammography: 3.49, ultrasonography: 3.06, cytology: 2.47 and physical examination: 1.67. The average age of the patients in the benign and malignant groups were the same: 58years. The two groups did not differ significantly over either distribution of coded mammographical results (p = 0.2092), or the distribution of mammographical parenchyma density patterns (p = 0.4875). However, the malignant and benign groups differed significantly from each other over the distribution of coded ultrasonographic (p = 0.0176) and cytological (p < 0.0001) results. In conclusion, in the preoperative diagnosis of asymptomatic “black-stars”, mammography detects the non-palpable lesions, and ultrasonography together with cytology proved better in the analysis, provided FNAB is US guided. Due to the complex diagnostic approach the nature of the “black stars” is known in the majority of cases prior to the surgical biopsy.

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Authors and Affiliations

  1. Mamma Breast Health Corporation, Kapás u. 29, Budapest, H-1023, Hungary

    Zsófia Egyed, Zoltán Péntek & Zsolt László

  2. 2nd Department of Pathology, Semmelweis University, Budapest, Hungary

    Balázs Járay & Janina Kulka

  3. Department of Surgery, Budai MAV Hospital, Budapest, Hungary

    Egon Svastics & József Kas

Authors
  1. Zsófia Egyed
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  2. Zoltán Péntek
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  3. Balázs Járay
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  4. Janina Kulka
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  6. József Kas
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  7. Zsolt László
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Correspondence to Zsófia Egyed.

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Egyed, Z., Péntek, Z., Járay, B. et al. Radial Scar-Significant Diagnostic Challenge. Pathol. Oncol. Res. 14, 123–129 (2008). https://doi.org/10.1007/s12253-008-9025-0

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  • DOI: https://doi.org/10.1007/s12253-008-9025-0

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