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NMR assignments of the human cytokine interleukin-33

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Abstract

We report near complete NMR backbone and side chain assignments of the human cytokine interleukin-33 (IL-33) in solution. IL-33 is the latest addition to the family of interleukin-1 homologous cytokines and was shown to be involved in inflammation and autoimmune diseases.

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Acknowledgments

We thank Borlan Pan (Genentech, South San Francisco) and Jeff G. Pelton (University of California, Berkeley) for technical help. The authors are employees of Genentech, Inc.

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  1. Department of Protein Engineering, Genentech, 1 DNA Way, South San Francisco, CA, 94080, USA

    Andreas Lingel & Wayne J. Fairbrother

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  1. Andreas Lingel
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  2. Wayne J. Fairbrother
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Correspondence to Wayne J. Fairbrother.

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Lingel, A., Fairbrother, W.J. NMR assignments of the human cytokine interleukin-33. Biomol NMR Assign 3, 223–225 (2009). https://doi.org/10.1007/s12104-009-9180-6

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  • DOI: https://doi.org/10.1007/s12104-009-9180-6

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