Skip to main content
Log in

Intraductal papillary mucinous neoplasm

  • Published:
Current Treatment Options in Gastroenterology Aims and scope Submit manuscript

Opinion statement

Surgical resection is the treatment of choice for intraductal papillary mucinous tumor. In intraductal papillary mucinous neoplasm, the extent of resection is determined by the extent of the disease. If, by pre- and intraoperative assessment, the disease appears localized, limited resection (pancreaticoduodenectomy or distal pancreatectomy) should be performed, ensuring that frozen sections show negative margins. Total pancreatectomy should be considered for extensive disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References and Recommended Reading

  1. Solcia E, Kloppel G: Tumors of the Pancreas. 3rd Series ed. Vol. Fascicle 20 Washington DC: Armed Forces Institute of Pathology; 1997. Excellent review of the pathology of IPMN.

    Google Scholar 

  2. Longnecker DS, Hruban HR, Kloppel G: Intraductal papillary-mucinous neoplasms of the pancreas. In World Health Organization Classification of Tumors. Pathology and Genetics of tumrs of the Digestive System, edn 2. Edited by Hamilton SR, Aaltonen LA. Lyon, France: IARC Press; 2000:237–240.

    Google Scholar 

  3. Conley CR, Scheithauer BW, van Heerden JA, Weiland LH: Diffuse intraductal papillary adenocarcinoma of the pancreas. Ann Surg 1987, 205:246–249.

    Article  PubMed  CAS  Google Scholar 

  4. Itai Y, Kokubo T, Atomi Y, et al.: Mucin-hypersecreting carcinoma of the pancreas. Radiology 1987, 165:51–55.

    PubMed  CAS  Google Scholar 

  5. Rickaert F, Cremer M, Deviere J, et al.: Intraductal mucin-hypersecreting neoplasms of the pancreas. A clinicopathologic study of eight patients. Gastroenterology 1991, 101:512–519.

    PubMed  CAS  Google Scholar 

  6. Yamada M, Kozuka S, Yamao K, et al.: Mucin-producing tumor of the pancreas. Cancer 1991, 68:159–168.

    Article  PubMed  CAS  Google Scholar 

  7. Raijman I, Kortan P, Walden D, et al.: Mucinous ductal ectasia: cholangiopancreatographic and endoscopic findings. Endoscopy 1994, 26:303–307.

    Article  PubMed  CAS  Google Scholar 

  8. Morohoshi T, Kanda M, Asanuma K, Kloppel G: Intraductal papillary neoplasms of the pancreas. A clinicopathologic study of six patients. Cancer 1989, 64:1329–1335.

    Article  PubMed  CAS  Google Scholar 

  9. Morohoshi T, Held G, Kloppel G: Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases. Histopathology 1983, 7:645–661.

    Article  PubMed  CAS  Google Scholar 

  10. Loftus EV Jr, Olivares-Pakzad BA, Batts KP, et al.: Intraductal papillary-mucinous tumors of the pancreas: clinicopathologic features, outcome, and nomenclature. Members of the Pancreas Clinic, and Pancreatic Surgeons of Mayo Clinic. Gastroenterology 1996, 110:1909–1918. Case series with a good review of various aspects of IPMN.

    Article  PubMed  Google Scholar 

  11. Rivera JA, Fernandez-del Castillo C, Pins M, et al.: Pancreatic mucinous ductal ectasia and intraductal papillary neoplasms. A single malignant clinicopathologic entity. Ann Surg 1997, 225:637–644; discussion 644–646. A case series compares subjects with IPMN with and without mucin hypersecretion. Dr. Warshaw discusses his approach to IPMN.

    Article  PubMed  CAS  Google Scholar 

  12. Traverso LW, Peralta EA, Ryan JA Jr, Kozarek RA: Intraductal neoplasms of the pancreas. Am J Surg 1998, 175:426–432.

    Article  PubMed  CAS  Google Scholar 

  13. Azar C, Van de Stadt J, Rickaert F, et al.: Intraductal papillary mucinous tumours of the pancreas. Clinical and therapeutic issues in 32 patients. Gut 1996, 39:457–464.

    PubMed  CAS  Google Scholar 

  14. Fukukura Y, Fujiyoshi F, Sasaki M, et al.: Intraductal papillary mucinous tumors of the pancreas: thinsection helical CT findings. AJR Am J Roentgenol 2000, 174:441–447.

    PubMed  CAS  Google Scholar 

  15. Cellier C, Cuillerier E, Palazzo L, et al.: Intraductal papillary and mucinous tumors of the pancreas: accuracy of preoperative computed tomography, endoscopic retrograde pancreatography and endoscopic ultrasonography, and long-term outcome in a large surgical series. Gastrointest Endosc 1998, 47:42–49.

    Article  PubMed  CAS  Google Scholar 

  16. Shimizu Y, Yasui K, Morimoto T, et al.: Case of intraductal papillary mucinous tumor [noninvasive adenocarcinoma] of the pancreas resected 27 years after onset. Int J Pancreatol 1999, 26:93–98.

    PubMed  CAS  Google Scholar 

  17. Nagai E, Ueki T, Chijiiwa K, et al.: Intraductal papillary mucinous neoplasms of the pancreas associated with so-called “mucinous ductal ectasia.” Histochemical and immunohistochemical analysis of 29 cases. Am J Surg Pathol 1995, 19:576–589.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chari, S.T. Intraductal papillary mucinous neoplasm. Curr Treat Options Gastro 5, 339–344 (2002). https://doi.org/10.1007/s11938-002-0022-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11938-002-0022-1

Keywords

Navigation