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Treatment of seborrheic dermatitis: comparison of sertaconazole 2 % cream versus pimecrolimus 1 % cream

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Abstract

Objective

Seborrheic dermatitis (SD) is an inflammatory skin disorder affecting the scalp, face, and trunk. The treatment of SD is an important issue in dermatology. This study aimed at comparing the efficacy of sertaconazole 2 % cream versus pimecrolimus 1 % cream in the treatment of SD.

Methods

In this clinical trial study, 60 patients suffering from SD were studied. Thirty patients received local sertaconazole 2 % cream and in control group, 30 patients received pimecrolimus 1 % cream. Patients were recommended to use the cream twice a day for 4 weeks. At the beginning of referring and also 2 and 4 weeks after first visit, the patients were examined by a dermatologist to control improvement of clinical symptoms.

Results

The mean age of members of the sertaconazole and pimecrolimus groups was 30.12 ± 12.56 and 34.67 ± 10.98 years, respectively. The highest level of satisfaction (90 %) was observed 28 days after sertaconazole application since it was 80 % in pimecrolimus group. The relationship between patients’ satisfaction and receipt of sertaconazole cream (on the 28th day) was statistically significant (P = 0.006).

Conclusion

Sertaconazole 2 % cream may be an excellent alternative therapeutic modality for treating SD.

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Authors and Affiliations

  1. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

    M. Goldust

  2. Medicinal Chemistry, Shahid Beheshti University of Medical Sciences, Tabriz, Iran

    E. Rezaee

  3. Tabriz Azad University of Medical Sciences, Tabriz, Iran

    R. Raghifar

Authors
  1. M. Goldust
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  2. E. Rezaee
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  3. R. Raghifar
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Corresponding author

Correspondence to M. Goldust.

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Goldust, M., Rezaee, E. & Raghifar, R. Treatment of seborrheic dermatitis: comparison of sertaconazole 2 % cream versus pimecrolimus 1 % cream. Ir J Med Sci 182, 703–706 (2013). https://doi.org/10.1007/s11845-013-0960-8

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  • DOI: https://doi.org/10.1007/s11845-013-0960-8

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