Summary
To study the effect of titanium alloy cage on the treatment of the ischemic necrosis of femoral head in dog, the model of the ischemic necrosis of femoral head was made with the liquid nitrogen in 15 hybrid adult dogs. The titanium alloy cage made of a hollow cylinder was driven into the subchondral bone of necrotic femoral head via central channel. The dogs were divided into 3 groups, each group was sacrificed 3, 6, 12 weeks after the operation respectively. No collapse of femoral head was observed after the operation. The position of the cages was good on radiograph. Microscopically, the cancellous bone of necrotic femoral head rebuilt gradually and grew into cage. After 12 weeks of creeping substitution, the cancellous bone filled up the hollow cavity and holes of the cages. It is concluded that the titanium alloy cage can provide structural support for the subchondral bone and prevent collapse and can be used for the treatment of the ischemic necrosis of femoral head.
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References
Yang S H, Yang C, Xu W H et al. Avascular necrosis of the femoral head produced in rabbits by freezing. Orthopedic J Chin (Chinese), 2001,8(1):48–49
Takaoka T, Yoshioka T, Hosoya T et al. The repair process in experimentally induced avascular necrosis of the femoral head in dogs. Arch Orthop Traumat Surg, 1981,99:109–115
Leali A, Fetto J, Hale J J. Biostructural augmentation for the treatment of osteonecrosis: rationale, technique, and case example. J South Orthop Assoc, 2002,11(3):167–171
Salvati EA, Cornell CN. Long-term follow-up of total hip replacement in patients with avascular necrosis. Instr Course Lect, 1988,37:67–73
Mont M A, Jones L C, Einhorn T A et al. Osteonecrosis of the femoral head: potential treatment with growth and differentiation factors. Clin Orthop, 1998,9:314–335
Yang C, Yang S H. Core decompression of the femoral head for avascular necrosis. Orthopedic J Chin (Chinese), 2000,7(9):889–891
Wang Y, Zhao D W, Wang J F et al. Memorial metal ball for the treatment of avascular necrosis of femoral head. Chin J Surg (Chinese), 1998,36(10):579–581
Wang Y, Wang J F, Lu S B et al. Flexible cage implantation for treatment of advanced osteonecrosis of femoral head in adolescence. Chin J Orthop (Chinese), 2000,(20):295–298
Lin B, Wang Y, Zhao Weidong et al. Biomechanical study on the treatment of ischemic necrosis of the femoral head using memorial metal flexible cage in adult. Chin J Clin Anat (Chinese), 2002,2(20):150–152
Aluisio, F V, Urbaniak J R. Proximal femur fractures after free vascularized fibular grafting to the hip. Clin Orthop, 1998,356:192–201
Schneider W, Breitenseher M, Engel A et al. The value of core decompression in treatment of femur head necrosis. Orthopade, 2000,29(5):420–429
Simank H G, Graf J, Kerber A et al. Long-term effects of core decompression by drilling: demonstration of bone healing and vessel ingrowth in an animal study. Acta Anat, 1997,158(3):185–191
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Ruiying WANG, male, born in 1973, M.D., Ph.D.
This project was supported by a grant from the National Natural Sciences Foundation of China (No. 30170945).
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Wang, R., Gao, Y., Yang, S. et al. Titanium alloy cage implantation for the treatment of ischemic necrosis of femoral head in dogs. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 28, 163–166 (2008). https://doi.org/10.1007/s11596-008-0212-8
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DOI: https://doi.org/10.1007/s11596-008-0212-8