Abstract
Three new triterpenoid saponins, tomentoside A (1), B (2) and C (3), along with four known saponins (4–7) were isolated from the root of Anemone tomentosa. The structures of the new compounds were elucidated as 3-O-β-d-ribopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-α-l-arabinopyranosyl hederagenin 28-O-α-l-rhamnopyranosyl-(1→4)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside (1), 3-O-β-d-ribopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-xylopyranosyl hederagenin 28-O-α-l-rhamnopyranosyl-(1→4)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside (2) and 3-O-β-d-galactopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-β-d-xylopyranosyl oleanolic acid 28-O-α-l-rhamnopyranosyl-(1→4)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside (3) on the basis of chemical and spectral evidence. In the oligosaccharide chains of compound 3, the characteristic d-galactose residue is a rare structural feature and secondly encountered among triterpenoid saponins from Anemone.
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Acknowledgments
The authors thank Prof. Ji-tao Wang (Shaanxi University of Chinese Medicine) for the identification of plant materials, and Mr. Min-chang Wang (Nuclear Magnetic Resonance Center, Xi’an Modern Chemistry Research Institute) for the NMR measurements.
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Wang, Y., Kang, W., Hong, Lj. et al. Triterpenoid saponins from the root of Anemone tomentosa . J Nat Med 67, 70–77 (2013). https://doi.org/10.1007/s11418-012-0649-8
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DOI: https://doi.org/10.1007/s11418-012-0649-8