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Human T-cell leukemia virus type I: 25 years of progress and challenges

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Journal of Biomedical Science

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References

  • J.M. Bishop (1990) ArticleTitleNobel Lecture. Retroviruses and oncogenes II Biosci. Rep. 10 473–491

    Google Scholar 

  • B.J. Poiesz F.W. Ruscetti J.W. Mier A.M. Woods R.C. Gallo (1980) ArticleTitleT-cell lines established from human T-lymphocytic neoplasias by direct response to T-cell growth factor Proc. Natl. Acad. Sci. USA 77 6815–6819

    Google Scholar 

  • Y. Hinuma K. Nagata M. Hanaoka M. Nakai T. Matsumoto K.I. Kinoshita S. Shirakawa I. Miyoshi (1981) ArticleTitleAdult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera Proc. Natl. Acad. Sci. USA 78 6476–6480

    Google Scholar 

  • M. Yoshida I. Miyoshi Y. Hinuma (1982) ArticleTitleIsolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease Proc. Natl. Acad. Sci. USA 79 2031–2035

    Google Scholar 

  • T. Uchiyama J. Yodoi K. Sagawa K. Takatsuki H. Uchino (1977) ArticleTitleAdult T-cell leukemia: clinical and hematologic features of 16 cases Blood 50 481–492

    Google Scholar 

  • L. Guertler (2002) ArticleTitleVirus safety of human blood, plasma, and derived products Thromb. Res. 107 S39–S45

    Google Scholar 

  • T. Fujino Y. Nagata (2000) ArticleTitleHTLV-I transmission from mother to child J. Reprod. Immunol. 47 197–206

    Google Scholar 

  • S. Hino S. Katamine H. Miyata Y. Tsuji T. Yamabe T. Miyamoto (1996) ArticleTitlePrimary prevention of HTLV-I in Japan J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol. 13 S199–S203

    Google Scholar 

  • F.J. Kim N. Manel E.N. Garrido C. Valle M. Sitbon J.L. Battini (2004) ArticleTitleHTLV-1 and -2 envelope SU subdomains and critical determinants in receptor binding Retrovirology 1 41

    Google Scholar 

  • N. Manel F.J. Kim S. Kinet N. Taylor M. Sitbon J.L. Battini (2003) ArticleTitleThe ubiquitous glucose transporter GLUT-1 is a receptor for HTLV Cell 115 449–459

    Google Scholar 

  • K.T. Jeang C.Z. Giam M. Nerenberg G. Khoury (1987) ArticleTitleAbundant synthesis of functional human T-cell leukemia virus type I p40x protein in eucaryotic cells by using a baculovirus expression vector J. Virol. 61 708–713

    Google Scholar 

  • I. Azran Y. Schavinsky-Khrapunsky M. Aboud (2004) ArticleTitleRole of Tax protein in human T-cell leukemia virus type-I leukemogenicity Retrovirology 1 20

    Google Scholar 

  • Y.P. Ching A.C. Chun K.T. Chin Z.Q. Zhang K.T Jeang (2004) ArticleTitleSpecific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex. Retrovirology 1 18

    Google Scholar 

  • M. Matsuoka (2003) ArticleTitleHuman T-cell leukemia virus type I and adult T-cell leukemia Oncogene 22 5131–5140

    Google Scholar 

  • M. Yoshida (2001) ArticleTitleMultiple viral strategies of HTLV-1 for dysregulation of cell growth control Annu. Rev. Immunol. 19 475–496

    Google Scholar 

  • P.W. Ng H. Iha Y. Iwanaga M. Bittner Y. Chen Y. Jiang G. Gooden J.M. Trent P. Meltzer K.T. Jeang S.L. Zeichner (2001) ArticleTitleGenome-wide expression changes induced by HTLV-1 Tax evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation Oncogene 20 4484–4496

    Google Scholar 

  • K.T. Jeang (2001) ArticleTitleFunctional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B Cytokine Growth Factor 12 207–217

    Google Scholar 

  • K.T. Jeang C.Z. Giam F. Majone M. Aboud tax death (2004) ArticleTitleLife, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation J. Biol. Chem. 279 31991–31994

    Google Scholar 

  • A. Gessain F. Barin J.C. Vernant O. Gout L. Maurs A Calendar G. The Particlede (1985) ArticleTitleAntibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet 2 407–410

    Google Scholar 

  • M. Nagai M. Osame (2003) ArticleTitleHuman T-cell lymphotropic virus type I and neurological diseases J. Neurovirol. 9 228–235

    Google Scholar 

  • M. Osame A. Izumo A. Igata M. Matsumoto T. Matsumoto S. Sonoda M Tara Y. Shibata (1986) ArticleTitleBlood transfusion and HTLV-I associtated myelopathy Lancet 2 104–105

    Google Scholar 

  • B.N. Fields D.M. Knipe P.M. Howley D.E. Griffin (Eds) (2001) Field’s Virology, 4th edn. Lippincott Williams & Wilkins Philadelphia

    Google Scholar 

  • T. Akagi H. Ono K. Shimotohno (1996) ArticleTitleExpression of cell cycle regulatory genes in HTLV-I infected T-cell lines: possible involvement of Tax1 in the altered expression of cyclin D2, p18Ink4 and p21Waf1/Cip1/Sdi1 Oncogene 12 1645–1652

    Google Scholar 

  • R. Iwanaga K. Ohtani T Hayashi M. Nakamura (2001) ArticleTitleMolecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I. Oncogene 20 2055–2067

    Google Scholar 

  • K.V. Kibler K.T. Jeang (2001) ArticleTitleCREB/ATF-dependent repression of cyclin a by human T-cell leukemia virus type 1 Tax protein J.Virol. 75 2161–2173

    Google Scholar 

  • C. Neuveut D.Y. Jin O.J. Semmes F. Diella R. Callahan K.T. Jeang (1997) ArticleTitleDivergent subcellular locations of HTLV-I Tax and Int-6: a contrast between in vitro protein-protein binding and intracellular protein colocalization J. Biomed. Sci. 4 229–234

    Google Scholar 

  • K. Haller Y. Wu E. Derow I. Schmitt K.T. Jeang R. Grassmann (2002) ArticleTitlePhysical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein Mol. Cell. Biol. 22 3327–3338

    Google Scholar 

  • T. Akagi H. Ono N. Tsuchida K. Shimotohno (1997) ArticleTitleAberrant expression and function of p53 in T-cells immortalized by HTLV-I Tax1 FEBS Lett. 406 263–266

    Google Scholar 

  • A. Cereseto F. Diella J.C Mulloy A. Cara P. Michieli R. Grassmann G Franchini M.E. Klotman (1996) ArticleTitlep53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells Blood 88 1551–1560

    Google Scholar 

  • K.G. Low L.F. Dorner D.B. Fernando J. Grossman K.T. Jeang M.J. Comb (1997) ArticleTitleHuman T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a J. Virol. 71 1956–1962

    Google Scholar 

  • T. Suzuki S. Kitao H. Matsushime Yoshida M. (1996) ArticleTitleHTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4 EMBO J. 15 1607–1614

    Google Scholar 

  • C.A. Pise-Masison M. Radonovich K. Sakaguchi E. Appella J.N. Brady (1998) ArticleTitlePhosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells J. Virol. 72 6348–6355

    Google Scholar 

  • S. Takemoto R. Trovato A. Cereseto C. Nicot T. Kislyakova L. Casareto T. Waldmann G Torelli G. Franchini (2000) ArticleTitlep53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cells Blood 95 3939–3944

    Google Scholar 

  • P.L. Van K.W. Yim D.Y. Jin G. Dapolito A. Kurimasa K.T. Jeang (2001) ArticleTitleGenetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53 J. Virol. 75 396–407

    Google Scholar 

  • C. Neuveut K.G. Low F. Maldarelli I. Schmitt F. Majone R. Grassmann K.T. Jeang (1998) ArticleTitleHuman T-cell leukemia virus type 1 Tax and cycle progression: role of cyclin D-cdk and p110Rb Mol. Cell. Biol. 18 3620–3632

    Google Scholar 

  • A. Haoudi R.C. Daniels E. Wong G. Kupfer O.J. Semmes (2003) ArticleTitleHuman T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response J. Biol. Chem. 278 37736–37744

    Google Scholar 

  • B. Liu M.H. Liang Y.L. Kuo W. Liao I. Boros T. Kleinberger J. Blancato C.Z. Giam (2003) ArticleTitleHuman T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability Mol. Cell. Biol. 23 5269–5281

    Google Scholar 

  • Y. Iwanaga K.T. Jeang (2002) ArticleTitleExpression of mitotic spindle checkpoint protein hsMAD1 correlates with cellular proliferation and is activated by a gain-of-function p53 mutant Cancer Res. 62 2618–2624

    Google Scholar 

  • Y. Iwanaga T. Kasai K. Kibler KT. Jeang (2002) ArticleTitleCharacterization of regions in hsMAD1 needed for binding hsMAD2: a polymorphic change in an hsMAD1 leucine zipper affects MAD1-MAD2 interaction and spindle checkpoint function J. Biol. Chem. 277 31005–31012

    Google Scholar 

  • D.Y. Jin F Spencer KT. Jeang (1998) ArticleTitleHuman T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1 Cell 93 81–91

    Google Scholar 

  • T. Kasai Y. Iwanaga H. Iha K.T. Jeang (2002) ArticleTitlePrevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors J. Biol. Chem. 277 5187–5193

    Google Scholar 

  • O. Gout M. Baulac A. Gessain F. Semah F. Saal J. Peries C. Cabrol C. Foucault-Fretz D. Laplane F. Sigaux G. Dethe (1990) ArticleTitleRapid development of myelopathy after HTLV-I infection acquired by transfusion during cardiac transplantation New Engl. J. Med 322 383–388

    Google Scholar 

  • M. Kannagi T. Ohashi N. Harashima S. Hanabuchi A. Hasegawa (2004) ArticleTitleImmunological risks of adult T-cell leukemia at primary HTLV-I infection Trends Microbiol. 12 346–352

    Google Scholar 

  • B.J. Poiesz M.J. Poiesz D. Choi (2003) ArticleTitleThe human T-cell lymphoma/leukemia viruses Cancer Invest. 21 253–277

    Google Scholar 

  • T Kasai K.T. Jeang (2004) ArticleTitleTwo discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells Retrovirology 1 7

    Google Scholar 

  • M. Nagai M.B. Brennan J.A. Sakai C.A Mora S. Jacobson (2001) ArticleTitleCD8(+) T cells are an in vivo reservoir for human T-cell lymphotropic virus type I Blood 98 1858–1861

    Google Scholar 

  • J.H. Richardson A.J. Edwards J.K. Cruickshank P. Rudge A.G. Dalgleish (1990) ArticleTitleIn vivo cellular tropism of human T-cell leukemia virus type I J. Virol. 64 5682–5687

    Google Scholar 

  • K. Kehn L. Deng C. De La Fuente K. Strouss K. Wu A. Maddukuri S. Baylor R. Rufner A. Pumfery M.E Bottazzi F. Kashanchi (2004) ArticleTitleThe role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells Retrovirology 1 6

    Google Scholar 

  • M. Osame K. Usuku S. Izumo N. Ijichi H. Amitani A. Igata M Matsumot M. Tara (1986) ArticleTitleHTLV-I associated myelopathy, a new clinical entity Lancet 1 1031–1032 Occurrence Handle10.1016/S0140-6736(86)91298-5 Occurrence Handle1:STN:280:BimB3c3itl0%3D

    Article  CAS  Google Scholar 

  • Y. Schavinsky-Khrapunsky E. Gold Z. Ben Aroya A. Torgeman M. Aboud M. Huleihel (2003) ArticleTitleActivation of HTLV-I long terminal repeat by apoptosis inducing agents: mechanism and implications for HTLV-I pathogenicity (review) Int. J. Mol. Med. 11 3–11

    Google Scholar 

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Authors and Affiliations

  1. Center for Infectious Diseases and Vaccinology, Arizona State University, 85287, Tempe, AZ, USA

    Karen V. Kibler

  2. Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, 20892, MD, Bethesda, USA

    Kuan-Teh Jeang

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  1. Karen V. Kibler
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Kibler, K.V., Jeang, KT. Human T-cell leukemia virus type I: 25 years of progress and challenges. J Biomed Sci 12, 7–11 (2005). https://doi.org/10.1007/s11373-004-8164-x

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  • DOI: https://doi.org/10.1007/s11373-004-8164-x

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