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Ductal carcinoma in situ: knowledge of associated risks and prognosis among Latina and non-Latina white women

  • Epidemiology
  • Published:
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Abstract

While not itself life-threatening, ductal carcinoma in situ (DCIS) can progress to invasive disease if untreated, and confers an increased risk of future breast cancer. We investigated knowledge of DCIS among a cohort of English- and Spanish-speaking Latina and English-speaking non-Latina white women previously treated for DCIS. We examined knowledge of DCIS with four true/false statements about risk of invasive disease, breast cancer recurrence, and prognosis. For each knowledge statement, we modeled the odds of a correct answer by language–ethnicity (English-speaking Latinas, Spanish-speaking Latinas, and English-speaking whites) adjusting for demographics, health history, and treatment factors. Of 710 participants, 52 % were English-speaking whites, 21 % English-speaking Latinas, and 27 % Spanish-speaking Latinas. Less than half (41 %) of participants were aware that DCIS is not life-threatening and only 32 % knew that surgical treatment choice does not impact mortality; whereas two-thirds (67 %) understood that DCIS confers increased risk of future breast cancer, and almost all (92 %) knew that DCIS, if untreated, could become invasive. Only three Spanish-speakers used professional interpreters during discussions with their physicians. In adjusted analyses, compared to English-speaking whites, both English- and Spanish-speaking Latinas had significantly lower odds of knowing that DCIS was not life-threatening (OR, 95 % CI 0.6, 0.4–0.9 and 0.5, 0.3–0.9, respectively). In contrast, Spanish-speaking Latinas had a twofold higher odds of knowing that DCIS increases risk of future breast cancer (OR, 95 % CI 2.6, 1.6–4.4), but English-speaking Latinas were no different from English-speaking whites. Our data suggest that physicians are more successful at conveying the risks conferred by DCIS than the nuances of DCIS as a non-life-threatening diagnosis. This uneven communication is most marked for Spanish-speaking Latinas. In addition to the use of professional interpreters, efforts to create culturally and linguistically standardized information could improve knowledge and engagement in informed decision making for all DCIS patients.

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Acknowledgments

This research was conducted with the support of the California Breast Cancer Research program (9 PB-0157). The collection of cancer incidence data used in this study was supported by the California Department of Public Health as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885; the National Cancer Institute’s Surveillance, Epidemiology and End Results Program under contract HHSN261201000140C awarded to the Cancer Prevention Institute of California, contract HHSN261201000035C awarded to the University of Southern California, and contract HHSN261201000034C awarded to the Public Health Institute; and the Centers for Disease Control and Prevention’s National Program of Cancer Registries, under agreement # U58DP003862-01 awarded to the California Department of Public Health. The ideas and opinions expressed herein are those of the author(s) and endorsement by the State of California Department of Public Health, the National Cancer Institute, and the Centers for Disease Control and Prevention or their Contractors and Subcontractors is not intended nor should be inferred.

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Authors and Affiliations

  1. Division of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA

    Aparna R. Parikh

  2. Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA

    Aparna R. Parikh, Celia Patricia Kaplan, Nancy J. Burke & Leah S. Karliner

  3. Medical Effectiveness Research Center for Diverse Populations, University of California San Francisco, San Francisco, CA, USA

    Celia Patricia Kaplan, Jennifer Livaudais-Toman & Leah S. Karliner

  4. Division of General Internal Medicine, Department of Medicine, University of California San Francisco, 1545, Divisadero, San Francisco, CA, 94143-0320, USA

    Celia Patricia Kaplan, Jennifer Livaudais-Toman & Leah S. Karliner

  5. Division of Surgical Oncology, Department of Surgery, Duke University, Durham, NC, USA

    E. Shelley Hwang

  6. Department of Anthropology, History and Social Medicine, University of California San Francisco, San Francisco, CA, USA

    Nancy J. Burke

Authors
  1. Aparna R. Parikh
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  2. Celia Patricia Kaplan
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  3. Nancy J. Burke
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  4. Jennifer Livaudais-Toman
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  5. E. Shelley Hwang
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  6. Leah S. Karliner
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Corresponding author

Correspondence to Leah S. Karliner.

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Parikh, A.R., Kaplan, C.P., Burke, N.J. et al. Ductal carcinoma in situ: knowledge of associated risks and prognosis among Latina and non-Latina white women. Breast Cancer Res Treat 141, 261–268 (2013). https://doi.org/10.1007/s10549-013-2676-x

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  • DOI: https://doi.org/10.1007/s10549-013-2676-x

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