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Eccentrocytes in canine lipoma

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Abstract

The aim of this paper was to report a case of a female Rottweiler dog, 9 years old, presenting eccentrocytes in blood caused by the presence of a lipoma. This morphological change in red blood cells is considered uncommon, especially when related to cancer. The blood count revealed the presence of eccentrocytes, while the fine-needle aspiration cytology and histopathology of the nodule revealed to be a lipoma. Pre-surgical tests showed high levels of lipid peroxidation in the bloodstream, a parameter for assessment of oxidative stress, and increased antioxidant enzymes. Ten days after removal of the neoplasm, the values of lipid peroxidation and antioxidant enzymes decreased. One month after the surgery, there were no eccentrocytes in blood circulation. Thus, it appears that the occurrence of eccentrocytes in this case is linked to the presence of lipoma, which leads to an increase in lipid peroxidation and in antioxidant enzymes activities.

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Authors and Affiliations

  1. Department of Small Animal Clinic, University Veterinary Hospital, Federal University of Santa Maria, Santa Maria, Rio Grande do Sul, 97015-900, Brazil

    Paula Corrêa Venter, Raqueli Teresinha França, Estevan de Souza, Cinthia Melazzo Mazzanti & Sonia T. dos Anjos Lopes

  2. Veterinary Hospital, Center of Health Sciences, University of Cruz Alta, Cruz Alta, Rio Grande do Sul, 98005-050, Brazil

    Danieli Brolo Martins

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  1. Paula Corrêa Venter
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  2. Danieli Brolo Martins
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  3. Raqueli Teresinha França
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  4. Estevan de Souza
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  5. Cinthia Melazzo Mazzanti
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  6. Sonia T. dos Anjos Lopes
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Correspondence to Danieli Brolo Martins.

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Venter, P.C., Martins, D.B., França, R.T. et al. Eccentrocytes in canine lipoma. Comp Clin Pathol 23, 229–232 (2014). https://doi.org/10.1007/s00580-013-1816-3

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  • DOI: https://doi.org/10.1007/s00580-013-1816-3

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