Abstract
Introduction
Both enhanced recovery programs (ERP) and laparoscopy can reduce complications and length of stay (LOS) in colon surgery. We investigated whether ERP further improved the short-term outcomes of scheduled laparoscopic colectomies.
Methods
We performed an audit of all patients undergoing scheduled laparoscopic colon resection between January 2003 and August 2010 in our institution. An ERP including accelerated introduction of oral nutrition, mobilization, pain control, and catheter management was introduced in 2005. Demographic data, intra and postoperative details and 30-day ER visit and readmission rate were collected. We compared LOS and short-term outcomes for patients on the program with those receiving traditional postoperative care using Chi-square and regression models. Data are presented as median [25th, 75th percentile]. Statistical significance was defined as p < 0.05.
Results
136 (46 %) of 297 eligible patients were enrolled in the ERP. At baseline, the two groups had similar demographic characteristics, but patients in the ERP were more likely to have their operation by a colorectal surgeon (p = 0.01). Patients in the ERP ate solids earlier (p < 0.001) and had earlier removal of their urinary catheter (p < 0.001). LOS was 4 [3, 6] days for both groups (p < 0.01), with more patients in the ERP discharged by POD 3 (p < 0.001). After adjusting for other variables, ERP enrolment remained an independent predictor of LOS (p < 0.01), along with age (p < 0.01) and in-hospital complications (p < 0.001). Complication rates were similar between the two groups. Patients in the ERP had significantly fewer ER visits (p = 0.02), but there were no differences in readmission rates.
Conclusion
In patients undergoing scheduled laparoscopic colectomy in a university-based clinical teaching unit, ERP can further reduce length of stay and postoperative ER visits without increasing readmission rates.
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References
Reynolds WJ (2001) The first laparoscopic cholecystectomy. JSLS 5:89–94
Chung R, Pham Q, Wojtasik L, Chari V, Chen P (2003) The laparoscopic experience of surgical graduates in the United States. Surg Endosc 17:1792–1795
Schoetz DJ (2006) Evolving practice patterns in colon and rectal surgery. J Am Coll Surg 203:322–327
Eckert M, Cuadrado D, Steele S, Brown T, Beekley A, Martin M (2010) The changing face of the general surgeon: national and local trends in resident operative experience. Am J Surg 199:652–656
Takacs P, Chakhtoura N (2006) Laparotomy to laparoscopy: changing trends in the surgical management of ectopic pregnancy in a tertiary care teaching hospital. J Minim Invas Gynecol 13:175–177
Jacobs M, Verdeja JC, Goldstein HS (1991) Minimally invasive colon resection (laparoscopic colectomy). Surg Laparosc Endosc 1:144–150
Clinical Outcomes of Surgical Therapy Study Group (2004) A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 350:2050–2059
Bloomston M, Kaufman H, Winston J, Arnold M, Martin E (2005) Surgical management of colorectal cancer in the laparoscopic era: a review of prospective randomized trials. J Natl Compr Cancer Netw 3:517–524
Veldkamp R, Kuhry E, Hop WC, Jeekel J, Kazemier G, Bonjer HJ, Haglind E, Påhlman L, Cuesta MA, Msika S, Morino M, Lacy AM (2005) Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol 6:477–484
Reza MM, Blasco JA, Andradas E, Cantero R, Mayol J (2006) Systematic review of laparoscopic versus open surgery for colorectal cancer. Br J Surg 93:921–928
Schwenk W, Haase O, Neudecker J, Müller J (2005) Short term benefits for laparoscopic colorectal resection. Cochrane Database Syst Rev 3:CD00315
Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, Heath RM, Brown JM (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 365:1718–1726
Abraham N, Young J, Solomon M (2004) Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer. Br J Surg 91:1111–1124
Kehlet H (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606–617
Varadhan KK, Lobo DN, Ljungqvist O (2010) Enhanced recovery after surgery: the future of improving surgical care. Crit Care Clin 26:527–547
Wind J, Polle SW, Fung Kon Jin PHP, Dejong CHC, von Meyenfeldt MF, Ubbink DT, Gouma DJ, Bemelman WA (2006) Systematic review of enhanced recovery programmes in colonic surgery. Br J Surg 93:800–809
Adamina M, Kehlet H, Tomlinson GA, Senagore AJ, Delaney CP (2011) Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery 149:830–840
Khoo CK, Vickery CJ, Forsyth N, Vinall NS, Eyre-Brook IA (2007) A prospective randomized controlled trial of multimodal perioperative management protocol in patients undergoing elective colorectal resection for cancer. Ann Surg 245(6):867–872
Eskicioglu C, Forbes SS, Aarts MA, Okrainec A, McLeod RS (2009) Enhanced recovery after surgery (ERAS) programs for patients having colorectal surgery: a meta-analysis of randomized trials. J Gastrointest Surg 13:2321–2329
Spanjersberg WR, Reurings J, Keus F, van Laarhoven CJ (2011) Fast track surgery versus conventional recovery strategies for colorectal surgery. Cochrane Database Syst Rev CD007635
Khan S, Gatt M, MacFie J (2009) Enhanced recovery programmes and colorectal surgery: does the laparoscope confer additional advantages? Colorectal Dis 11:902–908
Vlug, Wind J, Hollmann MW, Ubbink DT, Cense HA, Engel AF, Gerhards MF, van Wagensveld BA, van der Zaag ES, van Geloven AAW, Sprangers MAG, Cuesta MA, Bemelman WA, group Ls (2011) Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 254:868–875. doi:810.1097/SLA.1090b1013e31821fd31821ce
Carli F, Charlebois P, Baldini G, Cachero O, Stein B (2009) An integrated multidisciplinary approach to implementation of a fast-track program for laparoscopic colorectal surgery. Can J Anesth 56:837–842
Seely AJ, Ivanovic J, Threader J, Al-Hussaini A, Al-Shehab D, Ramsay T, Gilbert S, Maziak DE, Shamji FM, Sundaresan RS (2010) Systematic classification of morbidity and mortality after thoracic surgery. Ann Thorac Surg 90:936–942 discussion; 942
Huynh TT, Miller CC 3rd, Estrera AL, Sheinbaum R, Allen SJ, Safi HJ (2002) Determinants of hospital length of stay after thoracoabdominal aortic aneurysm repair. J Vasc Surg 35:648–653
King PM, Blazeby JM, Ewings P, Franks PJ, Longman RJ, Kendrick AH, Kipling RM, Kennedy RH (2006) Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme. Br J Surg 93:300–308
Uchiyama K, Takifuji K, Tani M, Onishi H, Yamaue H (2002) Effectiveness of the clinical pathway to decrease length of stay and cost for laparoscopic surgery. Surg Endosc 16(11):1594–1597
Ishiguro S, Yamamoto S, Fujita S, Akasu T, Kobayashi Y, Moriya Y (2008) Effect of a clinical pathway after laparoscopic surgery for colorectal cancer. Hepatogastroenterology 55(85):1315–1319
Gouvas N, Tan E, Windsor A, Xynos E, Tekkis P (2009) Fast-track versus standard care in colorectal surgery: a meta-analysis update. Int J Colorectal Dis 24:1119–1131
Maessen J, Dejong C, Kessels A, von Meyenfeldt M, Group obotERAS (2008) Length of stay: an inappropriate readout of the success of enhanced recovery programs. World J Surg 32:971–975
Abraham NS, Young JM, Solomon MJ (2004) Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer. Br J Surg 91:1111–1124
Basse L, Jakobsen DH, Billesbølle P, Werner M, Kehlet H (2000) A clinical pathway to accelerate recovery after colonic resection. Ann Surg 232(1):51–57
Delaney CP, Senagore AJ, Gerkin TM, Beard TL, Zingaro WM, Tomaszewski KJ, Walton LK, Poston SA (2010) Association of surgical care practices with length of stay and use of clinical protocols after elective bowel resection: results of a national survey. Am J Surg 199:299–304
Andersen HK, Lewis SJ, Thomas S (2006) Early enteral nutrition within 24 h of colorectal surgery versus later commencement of feeding for postoperative complications. Cochrane Database Syst Rev 4
Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J, for the Enhanced Recovery After Surgery Study Group (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146:571–577
Delaney C (2008) Outcome of discharge within 24–72 h after laparoscopic colorectal surgery. Dis Colon Rect 51:181–185
Acknowledgement
The study was funded by a grant from Ethicon Canada.
Disclosures
Nicoleta O. Kolozsvari, Giovanni Capretti, Pepa Kaneva, Amy Neville, Franco Carli, Sender Liberman, Patrick Charlebois, Barry Stein, Melina C. Vassiliou, Gerald M. Fried, Liane S. Feldman have no conflicts of interest or financial ties to disclose.
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Kolozsvari, N.O., Capretti, G., Kaneva, P. et al. Impact of an enhanced recovery program on short-term outcomes after scheduled laparoscopic colon resection. Surg Endosc 27, 133–138 (2013). https://doi.org/10.1007/s00464-012-2446-6
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DOI: https://doi.org/10.1007/s00464-012-2446-6