Abstract
This work reports the allele frequencies for ten X-STRs (DXS8378, DXS7132, DXS9898, DXS6809, DXS9902, DXS6789, DXS7133, DXS7423, GATA172D05, GATA31E08) in a sample of 800 individuals from Paraná, Brazil. No deviations from the Hardy–Weinberg equilibrium were observed. Linkage disequilibrium analysis did not reveal association between the X-STRs. High overall power of discrimination was obtained for female and male samples, and high probability of exclusion was observed in father/mother/daughter trios and father/daughter duos. Genetic comparisons revealed significant differences between Paraná and other Brazilian populations.
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Tabbada KA, Ungria MCA, Faustino LP, Athanasiadou D, Stradmann-Bellinghausen B, Schneider PM (2005) Development of a pentaplex X-chromosomal short tandem repeat typing system and population genetic studies. Forensic Sci Int 154:173–180
Gomes I, Alves C, Maxzud K, Pereira R, Prata MJ, Sánchez-Diz P, Carracedo A, Amorim A, Gusmão L (2007) Analysis of 10 X-STRs in three African populations. Forensic Sci Int Genet 1:208–211
Robino C, Giolitti A, Gino S, Torre C (2006) Development of two multiplex PCR systems for the analysis of 12 X-chromosomal STR loci in a northwestern Italian population sample. Int J Leg Med 120:315–318
Cainé LM, Zarrabeitia MT, Riancho JA, Pinheiro MF (2010) Genetic data of a Brazilian population sample (Santa Catarina) using an X-STR decaplex. J Forensic Leg Med 17:272–274
Ribeiro-Rodrigues EM, Palha TJBF, Bittencourt EA, Ribeiro-dos-Santos A, Santos S (2011) Extensive survey of 12 X-STRs reveals genetic heterogeneity among Brazilian populations. Int J Leg Med 125:445–452
Gusmão L, Sánchez-Diz P, Alves C, Gomes I, Zarrabeitia MT, Abovich M, Atmetlla I, Bobillo C, Bravo L, Builes J, Cainé L, Calvo R, Carvalho E, Carvalho M, Cicarelli R, Catelli L, Corach D, Espinoza M, García O, Malaghini M, Martins J, Pinheiro F, Porto MJ, Raimondi E, Riancho JÁ, Rodríguez A, Rodríguez A, Cardozo AR, Schneider V, Silva S, Tavares C, Toscanini U, Vullo C, Whittle M, Yurrebaso I, Carracedo A, Amorim A (2009) A GEP–ISFG collaborative study on the optimization of an X-STR decaplex: data on 15 Iberian and Latin American populations. Int J Leg Med 123:227–234
Lareu MV, Phillips CP, Carracedo A, Lincoln PJ, Syndercombe Court D, Thomson JA (1994) Investigation of the STR locus HUMTH01 using PCR and two electrophoresis formats: UK and Galician Caucasian population surveys and usefulness in paternity investigations. Forensic Sci Int 66:41–52
Martins JÁ, Costa JC, Paneto GG, Figueiredo RF, Gusmão L, Sánchez-Diz P, Carracedo A, Cicarelli RMB (2010) Genetic profile characterization of 10 X-STRs in four populations of the southeastern region of Brazil. Int J Leg Med 124(5):427–432
Chakravarti A (1999) Population genetics: making sense out of a sequence. Nat Genet 21:56–60
Ribeiro-Rodrigues EM, Leite FPN, Hutz MH, Palha TJBF, Santos AKCR, Santos SEB (2008) A multiplex PCR for 11 X chromosome STR markers and population data from a Brazilian Amazon region. Forensic Sci Int Genet 2:154–158
Acknowledgments
The authors would like to acknowledge the Universidade Federal do Paraná, the Laboratório de Imunogenética e Histocompatibilidade and Polícia Científica do Paraná. This work was supported by the Fundação da Universidade Federal (FUNPAR).
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d`Avila Giacomel Kobachuk, L., Malaghini, M., da Silva, J.S. et al. Genetic profile characterization of ten X-STRs in a sample from Paraná, Brazil. Int J Legal Med 126, 975–976 (2012). https://doi.org/10.1007/s00414-012-0739-x
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DOI: https://doi.org/10.1007/s00414-012-0739-x