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Primary malignant mixed mullerian tumor of the vagina immunohistochemically confirmed

  • Case Report
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Abstract

Case report

We report the case of a 74-year old woman who presented with an ulcerated mass of the vagina. Histology of the tumor showed malignant mixed mullerian tumor (MMMT) with squamous and spindle cell stromal components, associated with high-grade vaginal intraepithelial neoplasia (VaIN 3). Immunohistochemical study of the neoplasm revealed that the malignant stromal tumor was a high-grade leiomyosarcoma. Despite the multimodal therapeutic approach, the patient died within 11 months.

Conclusion

The vagina is a rare site of presentation of primary MMMTs and the present case is the second one immunohistochemically confirmed.

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Authors and Affiliations

  1. Department of Pathology, “Alexandra” Hospital, Vassilissis Sophies 80, 115 28, Athens, Greece

    Maria Sotiropoulou

  2. 1st Department of Obstetrics and Gynecology, Gynecological Oncology Unit, “Alexandra” Hospital, Vassilissis Sophies 80, 115 28, Athens, Greece

    Dimitrios Haidopoulos, George Vlachos, Athanasios Pilalis, Alexandros Rodolakis & Emmanuel Diakomanolis

Authors
  1. Maria Sotiropoulou
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  2. Dimitrios Haidopoulos
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  3. George Vlachos
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  4. Athanasios Pilalis
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  5. Alexandros Rodolakis
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  6. Emmanuel Diakomanolis
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Corresponding author

Correspondence to Dimitrios Haidopoulos.

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Sotiropoulou, M., Haidopoulos, D., Vlachos, G. et al. Primary malignant mixed mullerian tumor of the vagina immunohistochemically confirmed. Arch Gynecol Obstet 271, 265–267 (2005). https://doi.org/10.1007/s00404-003-0582-x

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  • DOI: https://doi.org/10.1007/s00404-003-0582-x

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