Skip to main content

Advertisement

Log in

Modelling the spread of hepatitis C via commercial tattoo parlours: implications for public health interventions

  • Regular Article
  • Published:
OR Spectrum Aims and scope Submit manuscript

Abstract

Hepatitis C (HCV) is a serious infection caused by a blood-borne virus. It is a contagious disease spreading via a variety of transmission mechanisms including contaminated tattoo equipment. Effectively regulating commercial tattoo parlours can greatly reduce this risk. This paper models the cost-effectiveness and optimal timing of such interventions, and parameterises the model with data for Vienna, Austria. This dynamic model of the contagious spread of HCV via tattooing and other mechanisms accounts for secondary infections and shows that regulating tattoo parlours as done in Vienna, Austria in 2003, is a cost-saving intervention.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alter MJ (2002) Prevention of spread of hepatitis C. Hepatology 36(5 Suppl 1):S93–S98

    Article  Google Scholar 

  • American Gastroenterological Association (2003) Stigma of hepatitis C and lack of awareness stops Americans from getting tested and treated. AGA News Releases

  • Anderson RM, May RM (1991) Infectious diseases of humans. Oxford University Press, Oxford

    Google Scholar 

  • Armstrong ML, Murphy KP (1997) Tattooing: another adolescent risk behavior warranting health education. Appl Nurs Res 10(4):181–189

    Article  Google Scholar 

  • Armstrong ML, Roberts AE, Owen DC, Koch JR (2004) Contemporary college students and body piercing. J Adolescent Health 35(1):58–61

    Google Scholar 

  • Armstrong GL, Simard EP, Wasley A, McQuillan GM, Kuhnert WL, Alter MJ (2006) The prevalence of hepatitis C virus (HCV) infection in the United States, 1999–2002. Ann Internal Med 144(10):705–714

    Google Scholar 

  • Balasekaran R, Bulterys M, Jamal MM, Quinn PG, Johnston DE, Skipper B, Chaturvedi S, Arora S (1999) A case-control study of risk factors for sporadic hepatitis C virus infection in the southwestern United States. Am J Gastroenterol 94(5):1341–1346

    Article  Google Scholar 

  • Blaschke S, Purkert T (2004) Das ökonomische Potential von Präventionsmaßnahmen im Bereich Hepatitis C: Die Rolle der Tattoo-Studios. Master Thesis. University of Vienna, Austria

  • Centers for Disease Control and Prevention (1998) Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease. MMWR Morbid Mortal Wkly Rep 47(RR-19):1–33

    Google Scholar 

  • Centers for Disease Control and Prevention (2004) Hepatitis surveillance report no 59. US Department of Health and Human Services, CDC, Atlanta

  • Centers for Disease Control and Prevention (2005) Health Information for International Travel 2005–2006. Department of Health and Human Services, CDC, Atlanta

  • Commonwealth of Australia (2005) National hepatitis C strategy. 2005–2008. Publication approval number 3642 (JN9005). ISBN 0-642-82656-0

  • Desenclos JC (2003) The challenge of hepatitis C surveillance in Europe. Euro Surv 8(5):99–100

    Google Scholar 

  • Deuffic-Burban S, Poynard T, Valleron AJ (2002) Quantification of fibrosis progression in patients with chronic hepatitis C using a markov model. J Viral Hepatitis 9(2):114–122

    Article  Google Scholar 

  • Deuffic-Burban S, Wong JB, Valleron AJ, Costagliola D, Delfraissy JF, Poynard T (2004) Comparing the public health burden of chronic hepatitis C and HIV infection in France. J Hepatol 40(2):319–326

    Article  Google Scholar 

  • Esposito N, Rossi C (2004) A nested-epidemic model for the spread of hepatitis C among injecting drug users. Math Biosci 188:29–45

    Article  Google Scholar 

  • Federal Camber of Employees of the Republic of Austria (2004) Wirtschafts- und Sozialstatistisches Taschenbuch 2004. Federal Camber of Employees, Vienna, Austria

  • Federal Ministry of Economics and Labour of the Republic of Austria (2003) Ausuebungsregeln für das Piercen und Tätowieren durch Kosmetik (Schoenheitspflege)-Gewerbetreibende. BGBl II (Austrian Federal Law Gazette, Part II) 141/2003:647–651

  • Gold MR, Siegel JE, Russell LB, Weinstein MC (1996) Cost-effectiveness in health and medicine. Oxford University Press, New York

    Google Scholar 

  • Haley RW, Fischer RP (2001) Commercial tattooing as a potentially important source of hepatitis C infection. Clinical epidemiology of 626 consecutive patients unaware of their hepatitis C serologic status. Medicine 80(2):134–151

    Article  Google Scholar 

  • Haley RW, Fischer RP (2003) The tattooing paradox: are studies of acute hepatitis adequate to identify routes of transmission of subclinical hepatitis C infection? Archives of Internal Medicine 163(9):1095–1098

    Article  Google Scholar 

  • Health Canada (2001) Special report on youth, piercing, tattooing and hepatitis C trendscan findings. Health Canada, Toronto

  • Jacquez J, Koopman J, Perry T, Sattenspiel L, Simon C (1988) Modeling and analyzing HIV transmission: the effect of contact patterns. Math Biosci 92(2):119–199

    Article  Google Scholar 

  • Jonas S, Jessner W, Rafetseder O, Wild C (2004) Chronische Hepatitis C – Implikationen für Therapie und ökonomischen Ressourceneinsatz in Österreich. Institute for Technology Assessment of the Austrian Academy of Sciences, Vienna

    Google Scholar 

  • Kaplan EH, Brandeau M (eds) (1994) Modeling the AIDS epidemic. Raven Press, New York

    Google Scholar 

  • Layden TJ, Layden JE, Ribeiro RM, Perelson AS (2003). Mathematical modeling of viral kinetics: a tool to understand and optimise therapy. Clin Liver Dis 7(1):163–178

    Article  Google Scholar 

  • Mather D, Crofts N (1999) A computer model of the spread of hepatitis C virus among injecting drug users. Eur J Epidemiol 15(1):5–10

    Article  Google Scholar 

  • Mather D (2000) A simulation model of the spread of hepatitis C within a closed cohort. J Oper Res Soc 51(6):656–66

    Article  Google Scholar 

  • Nelson PW, Perelson AS (2002) Mathematical analysis of delay differential equation models of HIV-1 infection. Math Biosci 179(1):73–94

    Article  Google Scholar 

  • Pollack HA (2001) Cost-effectiveness of harm reduction in preventing hepatitis C among injection drug users. Med Decis Making 21(5):357–367

    Article  Google Scholar 

  • Pybus OG, Charleston MA, Gupta S, Rambaut A, Holmes EC, Harvey PH (2001) The epidemic behavior of the hepatitis C virus. Science 292(5525):2323–2325

    Article  Google Scholar 

  • Rauner MS (2002) Using simulation for AIDS policy modeling: benefits for HIV/AIDS prevention policy makers in Vienna, Austria. Health Care Manage Sci 5(2):121–134

    Article  Google Scholar 

  • Rauner MS, Brailsford SC, Flessa S (2005) The use of discrete-event simulation to evaluate strategies for the prevention of mother-to-child transmission of HIV in developing countries. J Oper Res Soc 56(2):222–233

    Article  Google Scholar 

  • Rauner MS, Behrens DA, Caulkins JP (2004) An epidemic model of the spread of hepatitis C via tattoo parlors: implications for the timing of public health interventions. ORDYS working paper 288, Vienna University of Technology, Vienna, Austria (37 p)

  • Salomon JA, Weinstein MC, Hammitt JK, Goldie SJ (2002) Empirically calibrated model of hepatitis C infection in the United States. Am J Epidemiol 156(8):761–773

    Article  Google Scholar 

  • Salomon JA, Weinstein MC, Hammitt JK, Goldie SJ (2003) Cost-effectiveness of treatment for chronic hepatitis C infection in an evolving patients population. JAMA 290(2):228–237

    Article  Google Scholar 

  • Sheerin IG, Green FT, Sellman JD (2003) The cost of not treating hepatitis C virus infection in injecting drug users in New Zealand. Drug Alcohol Rev 22(2):159–167

    Article  Google Scholar 

  • Siebert U, Sroczynski G, Rossol S, Wasem J, Ravens-Sieberer U, Kurth BM, Manns MP, Hutchison JG, Wong JB, German Hepatitis C Model (GEHMO) Group; International Hepatitis Interventional Therapy (IHIT) Group (2003) Cost-effectiveness of peginterferon α-2b plus ribavirin versus interferon α-2b plus ribavirin for initial treatment of chronic hepatitis C. Gut 52(3):425–432

    Article  Google Scholar 

  • Statistics Austria (2004) Statistic Yearbook 2004. Statistics Austria, Vienna

    Google Scholar 

  • Struve J, Norrbohm O, Stenbeck J, Giesecke J, Weiland O (1995) Risk factors for hepatitis A, B and C virus infection among Swedish expatriates. J Infect 31(3):205–209

    Article  Google Scholar 

  • Wasley A, Alter MJ (2000) Epidemiology of hepatitis C: geographic differences and temporal trends. Semin Liver Dis 20(1):1–16

    Article  Google Scholar 

  • Weusten JJ, van Drimmelen HA, Lelie PN (2003) Mathematic modeling of the risk of HBV, HCV, and HIV transmission by window-phase donations not detected by NAT. Transfusion 42(5):537–348

    Article  Google Scholar 

  • Wiese M, Berr F, Lafrenz M, Porst H, Oesen U (2000) Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: A 20-year multicenter study. Hepatology 32(1):91–96

    Article  Google Scholar 

  • World Health Organization (1999a) Hepatitis C—global prevalence (update). Wkly Epidemiol Rec 74(49):425–427

  • World Health Organization (1999b) Global surveillance and control of hepatitis C. Report of a WHO consultation organized in collaboration with the Viral Hepatitis Prevention Board: Antwerp, Belgium. J Viral Hepat 6(1):35–47

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marion S. Rauner.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Behrens, D.A., Rauner, M.S. & Caulkins, J.P. Modelling the spread of hepatitis C via commercial tattoo parlours: implications for public health interventions. OR Spectrum 30, 269–288 (2008). https://doi.org/10.1007/s00291-007-0090-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00291-007-0090-7

Keywords

Navigation