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Spiral CT quantification of aorto-renal calcification and its use in the detection of atheromatous renal artery stenosis: A study in 42 patients

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Abstract

Purpose: To investigate whether a correlation exists between aortic and renal arterial calcifications detected with spiral CT and significant angiographic renal artery stenosis (RAS).

Methods: Forty-two patients (mean age 67 years, range 37–84 years), of whom 24 were hypertensive, prospectively underwent abdominal helical CT and aortic and renal arteriography. The 3-mm thickness CT scans (pitch =1) were reconstructed each millimeter. A manual outline of the renal artery including its ostial portion was produced. Calcific hyperdensities were defined as areas of density more than 130 HU. CT data were compared with the presence or absence of RAS on angiography (24 cases); hypertension and age were taken into account (Mann-Whitney U-test).

Results: CT detection and quantification appeared to be reliable and reproductible. We did not find any correlation between aortic and renal arterial calcifications and RAS, even for the patients above 65 years, with or without hypertension. There was no correlation either between calcifications and hypertension in patients without RAS.

Conclusion: In this population, aortic and renal arterial calcifications have no predictive value for RAS.

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References

  1. Arad Y, Sparado L, Goodman K, Lledo-Perez A, Sherman S, Lerner G, Guerci AD (1996) Predictive value of electron beam computed tomography of the coronary arteries. Circulation 93:1951–1953

    PubMed  CAS  Google Scholar 

  2. Janowitz WR, Agatston AS, Viamonte M (1991) Comparison of serial quantitative evaluation of calcified coronary artery plaque by ultrafast computed tomography in persons with and without obstructive coronary artery disease. Am J Cardiol 68:1–6

    Article  PubMed  CAS  Google Scholar 

  3. Plainfosse MC, Boudeville JC, Serre V, Hernigou A, Challandre P, Simon A (1994) Dépistage et signication des calcifications coronaires. J Radiol 12:693–699

    Google Scholar 

  4. Simons DB, Schartz RS, Edwards WD, Sheedy PF, Breen JF, Rumberger JA (1992) Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: A quantitative pathologic comparison study. J Am Coll Cardiol 20:1118–1126

    PubMed  CAS  Google Scholar 

  5. Wexler L, Brundage B, Crouse J, Detrano R, Fuster V, Maddahi J, Rumberger J, Stanford W, White R, Taubert K (1996) Coronary artery calcification: Pathophysiology, epidemiology, imaging methods, and clinical implication. Circulation 94:1175–1192

    PubMed  CAS  Google Scholar 

  6. Wong ND, Vo AN, Abrahamson D, Tobis JM, Eisenberg H, Detrano RC (1994) Detection of coronary artery calcium by ultrafast computed tomography and its relation to clinical evidence of coronary artery disease. Am J Cardiol 73:223–227

    Article  PubMed  CAS  Google Scholar 

  7. Rubin GD, Dake MD, Napel SA, McDonnell CH, Jeffrey RB Jr (1993) Three dimensional spiral CT angiography of the abdomen: Initial clinical experience. Radiology 186:147–152

    PubMed  CAS  Google Scholar 

  8. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M Jr, Detrano R (1990) Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15:827–832

    Article  PubMed  CAS  Google Scholar 

  9. Agatston AS, Janowitz WR, Kaplan G, Gasso J, Hildner F, Viamonte M Jr (1994) Ultrafast computed tomography-detected coronary calcium reflects the angiographic extent of coronary arterial atherosclerosis. Am J Cardiol 74:1272–1274

    Article  PubMed  CAS  Google Scholar 

  10. Moynahan K, Yoshino BA (1993) Aortic and renal atherosclerotic calcifications seen on computed tomography of the spine: A positive predictor of hypertension. Invest Radiol 28:811–813

    Article  PubMed  CAS  Google Scholar 

  11. Siegel CL, Ellis JH, Korobkin N, Dunnick NR (1994) CT-detected renal arterial calcification: Correlation with renal artery stenosis on angiography. AJR 163:867–872

    PubMed  CAS  Google Scholar 

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Gayard, P., Garcier, JM., Boire, JY. et al. Spiral CT quantification of aorto-renal calcification and its use in the detection of atheromatous renal artery stenosis: A study in 42 patients. Cardiovasc Intervent Radiol 23, 17–21 (2000). https://doi.org/10.1007/s002709910003

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