Abstract
The authors describe a case of primary thrombocythemia and thrombosis of the adrenal vessels which they were able to examine by arteriography of the renal and adrenal arteries, by adrenal CT and at autopsy following the patient’s death. The available research data and hypotheses concerning the pathogenesis of thrombosis and hemorrhage in thrombocythemia are reviewed, but the relationship between platelet number and function and the incidence of thrombotic and hemorrhagic complications has not yet been clearly established. Pathogenesis of thrombosis and hemorrhage in suprarenal vessels is not clear and the majority of authors postulate early venous damage.
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Barbui T., Cortelazzo S., Viero P., Bassan R., Dini E., Semeraros N. Thrombohemorrhagic complications in 101 cases of myeloproliferative disorders: relationship to platelet number and function. Eur. J. Cancer Clin. Oncol. 19: 1593, 1983.
Davis R.B. Acute thrombotic complications of myeloproliferative disorders in young adults. Am. J. Clin. Pathol. 84: 180, 1985.
Murphy S. Thrombocytosis and thrombocythemia. Clin. Haematol. 12: 89, 1983.
Preston F.E., Emmanuel J.G., Winfield D.A., Malia R.G. Essential thrombocythemia and peripheral gangrene. Br. Med. J. 3: 548, 1974.
Singh A.K., Wetherley-Mein G. Microvascular occlusive lesion in primary thrombocythemia. Br. J. Haematol. 36: 553, 1977.
Randi M.L., Fabris F., Girolami A. Thrombocytosis in young people: evaluation of 57 cases diagnosed before the age of 40. Blut 60: 233, 1990.
Randi M.L., Casonato A., Fabris F., Vito C., Girolami A. The significance of thrombocytosis in old age. Acta Haematol. 78: 41, 1987.
Schafer A.I. Bleeding and thrombosis in the myeloproliferative disorders. Blood 64: 1, 1984.
De Maria M., Lanconi A., Lagalla R. Diagnostic images of adrenal glands. La Radiologia Medica 75: 219, 1988.
Lindvall N., Slezak P. Arteriography of the adrenals. Radiology 99: 999, 1969.
Losinno F., Barozzi L. Adrenal angioma. La Radiologia Medica 76: 228, 1988.
Roversi R., Golfieri R., Rossi C., Gemelli G. Digital subtraction angiography of renal and adrenal vessels. Applications and suggestions. La Radiologia Medica 71: 740, 1985.
Ziosi A. Clinical experiences of digital subtraction angiography. Aulo Gaggi Editore, Bologna, Aprile 1990, p. 107.
Fox B. Venous infarction of the adrenal glands. Journal Pathol. 119: 65, 1976.
Berte S.J. Spontaneous adrenal hemorrhage in the adult: Literature review and report of two cases. Ann. Int. Med. 38: 28, 1953.
Mitchell N., Angrist A. Focal necrosis of the adrenal cortex. Am. J. Med. Sciences 205: 549, 1943.
Botteri A., Orell S.R. Adrenal hemorrhage and necrosis in the adult: A clinicopathological study of 23 cases. Acta Med. Scand. 175, 4: 409, 1964.
Hutt M.S.R., Pinniger J.L. Adrenal failure due to bilateral suprarenal infarction associated with systemic nodular panniculitis and endoarteritis. J. Clin. Pathol. 9: 316, 1956.
Sheenhan H.L. Infarctus hémorragique du cortex surrénal dans la grossesse. Ann. Endocrinol. (Paris) 16: 687, 1955.
Thrash A.M., Iri H. Adrenal infarction six cases reports. Arch. Pathol. 75: 538, 1963.
Greendyke R.M. Adrenal hemorrhage. Am. J. Clin. Pathol. 43: 210, 1965.
Ling D., Korobkin M., Silverman P.M., Dunnick N.R. CT demonstration of bilateral adrenal hemorrhage. AJR 141: 307, 1983.
Siu S.C.B., Kitzman D.W., Sheedy P.F., Northcutt R.C. Adrenal insufficiency from bilateral adrenal hemorrhage. Mayo Clin. Proc. 65: 664, 1990.
Wolverson M.K., Kannegeiser H. CT of bilateral adrenal hemorrhage with acute adrenal insufficiency in the adult. AJR 1542: 311, 1984.
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Barillari, B., Shapiro, B., Gasparini, D. et al. Thrombocythemia and thrombosis of the adrenal vessels. J Endocrinol Invest 16, 345–349 (1993). https://doi.org/10.1007/BF03348854
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DOI: https://doi.org/10.1007/BF03348854