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Studies on the use of aluminum hydroxide gel in the treatment of peptic ulcer

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The American Journal of Digestive Diseases

Summary And Conclusions

Twelve patients with peptic ulcer have been treated by colloidal aluminum hydroxide. This was given orally or by a combination of a continuous drip and oral method. It was found that the gastric contents can be neutralized completely by this therapy. Relief of pain occurred within 24 hours. In addition to neutralizing the secreted acid, the drug decreased the titratable acidity. Patients with a marked hypersecretion were brought under satisfactory control. No adverse effects have been noted by the treatment. It is suggested that this form of therapy will be useful particularly in treating patients with a marked hypersecretion who formerly have been difficult to control by the usual alkaline powders.

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Emery, E.S., Rutherford, R.B. Studies on the use of aluminum hydroxide gel in the treatment of peptic ulcer. American Journal of Digestive Diseases 5, 486–492 (1938). https://doi.org/10.1007/BF02997083

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  • DOI: https://doi.org/10.1007/BF02997083

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