Skip to main content
Log in

Inflammatory fibroid polyps of gastro-intestinal tract

  • Clinical Observation
  • Published:
Chinese Journal of Cancer Research

Abstract

Objective: To review the diagnosis and differential diagnosis of inflammatory fibroid polyp (IFP) of gastrointestinal tract. Methods: The clinical symptoms, histopathologic features and immunohistochemical (ABC method) staining in 9 cases were observed. Results: IFP presented either as a solitary pedunculated or sessile lesion arising from the submucosa and protroding into the lumen; composed of a background of fibroblasts and blood vessels infiltrated by a variable number of inflammatory cells, often numerous eosinophilias leukocytes. Immunohistochemical staining: the spindle cells of all cases reacted with Vimentin. The partial cells of several cases react with Actin, NSE, a -AT. 7 cases were follow-up. No patients had a recurrence of the lesion. Conclusion: IFP are rare lesions, and may represent an exaggerated response to inflammatory or other injury process. The prognosis is good when treated by segmental resections of endoscopic removals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Vanek J. Gastric submucosal granuloma with eosinophilic infiltration. Am J Pathol 1949; 25: 397.

    PubMed  CAS  Google Scholar 

  2. Helwig EB, Ranier A. Inflammatory fibroid polyps of the stomach. Surg Gynecol Obstet 1953; 96: 355.

    Google Scholar 

  3. Stolte M, Sticht T, Eidt S, et al. Frequency, location, and age and sex distribution of various type of gastric polyp. Endoscopy 1994; 26: 659.

    Article  PubMed  CAS  Google Scholar 

  4. Tada S, lida M, Yao T, et al. Endoscopic removal of inflammatory fibroid polyps of the stomach. Am J Gastrotero 1991; 86: 1247.

    CAS  Google Scholar 

  5. Matsushita M, Hajiro K, Okazaki K, et al. Gastric inflammatory fibroid polyps: endoscopic ultrasonographic analysis in comparison with the histology. Gastrointestinal Endoscopy 1997; 46: 53.

    Article  PubMed  CAS  Google Scholar 

  6. Kim YI, Kim WH. Inflammatory fibroid polyps of gastrointestinal tract. Am J Clin Pathol 1988; 89: 721.

    PubMed  CAS  Google Scholar 

  7. Navas-Palacios JJ, Colina-Ruizdelgado F, Sanchez-Larrea MD, et al. Inflammatory fibroid polyps of the gastrointestinal tract: An immunohistochemical and electron microscopic study. Cancer 1983; 51: 1682.

    Article  PubMed  CAS  Google Scholar 

  8. Matsushita M, Hajiro K, Okazaki K, et al. Endoscopic feature of gastric inflammatory fibroid polyps. Am J gastroenter 1996; 91: 1595.

    PubMed  CAS  Google Scholar 

  9. Shimer GR, Helwing ES. Inflammatory fibroid polyps of the intestine. Am J Clin pathol 1984; 81: 708.

    PubMed  CAS  Google Scholar 

  10. Watanabe H, Jass JR, Sobin LH. WHO Histological Typing of Oesophageal and Gastric Tumor. 2nd ed. Hong Kong: Springer-Verlag, 1990; P37.

    Google Scholar 

  11. Myint MA, Medeiros JM, Sulaiman RA, et al. Inflammatory pseudotumor of the ileum: Areport of a multifocal, transmural lesion with regional lymph node involvement. Arch Pathol Lab Med 1994; 118: 1138.

    PubMed  CAS  Google Scholar 

  12. Wright JR, Kyriakos M, DeSchryver-Kecskemeti K. Malignant fibrous histiocytoma of the stomach. Arch Pathol Lab Med 1988; 112: 251.

    PubMed  Google Scholar 

  13. Meis IM, Enzinger FM. Inflammatory fibrosarcoma of the mesentery and retroperitoneum: a tumor closely simulating inflammatory pseudotumor. Am J Surg Pathol 1991; 15: 146.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Meng Fan-qing.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Meng, Fq., Qian, Cy. & Huang, Z. Inflammatory fibroid polyps of gastro-intestinal tract. Chin J Cancer Res 12, 138–140 (2000). https://doi.org/10.1007/BF02983441

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02983441

Key words

Navigation