Summary
Fluid from a pleural effusion in a child with malignant histiocytosis was grafted into nude mice. Cytogenetic studies were performed on the xenografted cells which revealed a diploid karyotype with a translocation t (5; 6) and a marker (13q +). This study reports a new rearrangement which has not been described previously in malignant histiocytosis.
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Soulie, J., Rousseau-Merck, MF., Mouly, H. et al. Cytogenetic study of malignant histiocytosis transplanted into nude mice; presence of translocation between chromosomes 5 and 6 and a unique marker (13q+). Virchows Archiv B Cell Pathol 50, 339–344 (1986). https://doi.org/10.1007/BF02889912
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DOI: https://doi.org/10.1007/BF02889912